GENETICS(LL)-W/CONNECT >CUSTOM<
6th Edition
ISBN: 9781260571561
Author: HARTWELL
Publisher: MCG CUSTOM
expand_more
expand_more
format_list_bulleted
Concept explainers
Videos
Textbook Question
Chapter 12, Problem 10P
Which of the following would be suggested by a DNase hypersensitive site?
| a. | No transcription occurs in this region of the chromosome. |
| b. | The chromatin is in a more open state than a region without the hypersensitive site. |
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
Answer the following concisely:
a. Where does transcription begin?
b. What are the template and coding strands of DNA?
c. Why only one strand transcribed?
d. Is the same strand of DNA always transcribed?
Loosening the chromatin structure occurs because of
Select one:
a. Lysine methylation
b. Lysine acetylation
c. Lysine phosphorylation
d. Lysine sumoylation
Research has shown that more mutations accumulate in regions of a chromosome that consist of compact chromatin, such as heterochromatin. Offer an explanation for why mutation rates would be higher where chromatin is more compact.
Chapter 12 Solutions
GENETICS(LL)-W/CONNECT >CUSTOM<
Ch. 12 - For each of the terms in the left column, choose...Ch. 12 - Many proteins other than histones are found...Ch. 12 - What difference exists between the compaction of...Ch. 12 - What is the role of the core histones in...Ch. 12 - a. About how many molecules of histone H2A would...Ch. 12 - The enzyme micrococcal nuclease can cleave...Ch. 12 - a. What letters are used to represent the short...Ch. 12 - About 2000 G bands are visible in a...Ch. 12 - Suppose you performed a fluorescence in situ...Ch. 12 - Which of the following would be suggested by a...
Ch. 12 - For each of the following pairs of chromatin...Ch. 12 - a. Drosophila b. Humans Give examples of...Ch. 12 - One histone modification that is seen consistently...Ch. 12 - Recently, scientists constructed a transgene that...Ch. 12 - Drosophila geneticists have isolated many...Ch. 12 - On the following figures, genes A and B are on the...Ch. 12 - Prob. 17PCh. 12 - The first page of this chapter displays photos of...Ch. 12 - The human genome contains about 3 billion base...Ch. 12 - The mitotic cell divisions in the early embryo of...Ch. 12 - In an experiment published in the journal Cell in...Ch. 12 - a. What DNA sequences are found at the telomeres...Ch. 12 - Prob. 23PCh. 12 - a. In a fluorescent in situ hybridization FISH...Ch. 12 - If you are comparing the two telomeres in each...Ch. 12 - a. What DNA sequences are commonly found at human...Ch. 12 - On the graphs presented in Problem 21, no data is...Ch. 12 - Prob. 29PCh. 12 - Prob. 30PCh. 12 - In the 1920s, Barbara McClintock, later a Nobel...Ch. 12 - Give at least one example of a chromosomal...Ch. 12 - Cornelia de Lange syndrome CdLS is a rare human...Ch. 12 - a. Give at least three examples of types of...Ch. 12 - A number of yeast-derived elements were added to...Ch. 12 - Prob. 36PCh. 12 - The completely synthetic yeast chromosome Syn III...
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Histones form more accessible chromatin because of Select one: a. Reduced electrostatic attraction between the histone and the negatively charged DNA backbone b. Increased electrostatic attraction between the histone and the negatively charged DNA backbone c. Reduced covalent bonding between the histone and the negatively charged DNA backbone d. Increased covalent bonding between the histone and the negatively charged DNA backbonearrow_forwardWhen chromatin is treated with non-specific nucleases, what is the length of the resulting pieces of DNAarrow_forwardEuchromatin refers to regions of DNA that are loosely packed to increase the efficiency of transcription. Which of the following would you expect to find in a region of euchromatin? A. more thymines B. fewer thymines C. more histones D. fewer histonesarrow_forward
- The term heterochromatin refers to heavily condensed regions of chromosomes that are largely devoid of genes. Since few genes exist there, these regions almost never decondense for transcription. At what point during the cell cycle would expect to observe decondensation of heterochromatic regions? Why?arrow_forwardA mutant DNA strand was transcribed then translated to proteins. a. What is the protein product of the mutant DNA strand? The sequence of the mutant strand is shown below: 5'-TGCCATAACTGTTCGTACTGGCAAATTGCC-3' 3'-ACGGTATTGACAAGCATGACCGTTTAACGG-5' b. The mutation altered the sequence of the wild type template DNA such that a degenerate codon for a basic amino acid in the wild type was converted to a non-degenerate codon resulting in the sequence for the mutant strand shown. What was the original amino acid? c. Compare the charges and pl of the mutant peptide and the normal (wild- type) peptide at physiological pH?arrow_forwardWhich illustration below correctly depicts the effect of histone modification in chromatin remodeling? (Ac- acetyl group, -H3K9trimethylated)? Ac Ac AC AC AC A. m 2 Ac Ac Ac Ac B. C. Ac Ac H3K9trimethylated Ac Ac Acarrow_forward
- Consider how histone proteins bind to DNA and then explain whya high salt concentration can remove histones from DNA (asshown in 10.18b).arrow_forwardFor each statement below indicate whether it is true or false: A. Strand discrimination during the process of DNA repair is based on DNA methylation B. The genetic code has 64 amino acid-specifying codons C. Mutations in germline cells are more consequential to subsequent generations than mutations in somatic cells.arrow_forwardHow does KU proteins promote DNA repair during mitosis? Explain.arrow_forward
- Suppose a chemist develops a new drug that neutralizes the positive charges on the tails of histone proteins. What would be the most likely effect of this new drug on chromatin structure? Would this drug have any effect on gene expression? Explain your answers.arrow_forwardGive Detailed explanation Solution (don't give Handwritten answer)arrow_forwardDescribe the mechanism by which histone modifications are established after DNA replication and cell division. What are some things that could go wrong if modifications can't be maintained? Think about what histone modifications do to DNA and why cells maintain parts of their chromosome as heterochromatin.arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Essentials of Pharmacology for Health ProfessionsNursingISBN:9781305441620Author:WOODROWPublisher:Cengage
Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage Learning
Essentials of Pharmacology for Health Professions
Nursing
ISBN:9781305441620
Author:WOODROW
Publisher:Cengage
Human Heredity: Principles and Issues (MindTap Co...
Biology
ISBN:9781305251052
Author:Michael Cummings
Publisher:Cengage Learning
12DaysinMarch, Genital Infections for USMLE Step One; Author: Howard Sachs;https://www.youtube.com/watch?v=66zR_FypVFQ;License: Standard youtube license