GENETICS(LL)-W/CONNECT >CUSTOM<
6th Edition
ISBN: 9781260571561
Author: HARTWELL
Publisher: MCG CUSTOM
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Chapter 12, Problem 8P
About 2000 G bands are visible in a high-resolution karyotype of the 3 billion base pairs in the haploid human genome. If the genome contains about 27,000 genes, about how many genes would be removed by a deletion of DNA that could be detected by karyotype analysis?
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Although DNA transposons are abundant in the genomes of multicellular eukaryotes, class 1 elements usually make up the largest fraction of very large genomes such as those from humans (~2500 Mb), maize (~2500 Mb), and barley (~5000 Mb). Given what you know about class 1 and class 2 elements, what is it about their distinct mechanisms of transposition that would account for this consistent difference in abundance?
Using a laser beam, you isolated several R bands from human chromosomes. Answer the following questions
What kinds of genes are present in R bands?
Which isochors do you expect to be present in the R band?
What class of interspersed repeats will be present in R bands?
What class of tandem repeats do you expect to find in RG bands?
Would you expect to find telomere sequences in some R bands?
A diploid (ie, contains TWO sets of chromosomes) organisms with a 45,000-kb haploid (counts only one set of its chromosomes) genome contains 21% G residues. Calculate the number of A, C, G< and T residues in the DNA of each cell in this organism.
Can you help explain why this is the answer, thank you!
Answer: Since the haploid genome contains 21% G, it must contain 21% C (Because G=C) and 58% A + T, or 29% A and 29% T. Each cell is a diploid, containing 90,000 kb or 9x10^7 bases. Therefore, A=T = (0.29)(9x10^7) = 2.61 x 10^7 bases and G=C=(0.21)(9x10^7) = 1.89x10^7 bases.
Chapter 12 Solutions
GENETICS(LL)-W/CONNECT >CUSTOM<
Ch. 12 - For each of the terms in the left column, choose...Ch. 12 - Many proteins other than histones are found...Ch. 12 - What difference exists between the compaction of...Ch. 12 - What is the role of the core histones in...Ch. 12 - a. About how many molecules of histone H2A would...Ch. 12 - The enzyme micrococcal nuclease can cleave...Ch. 12 - a. What letters are used to represent the short...Ch. 12 - About 2000 G bands are visible in a...Ch. 12 - Suppose you performed a fluorescence in situ...Ch. 12 - Which of the following would be suggested by a...
Ch. 12 - For each of the following pairs of chromatin...Ch. 12 - a. Drosophila b. Humans Give examples of...Ch. 12 - One histone modification that is seen consistently...Ch. 12 - Recently, scientists constructed a transgene that...Ch. 12 - Drosophila geneticists have isolated many...Ch. 12 - On the following figures, genes A and B are on the...Ch. 12 - Prob. 17PCh. 12 - The first page of this chapter displays photos of...Ch. 12 - The human genome contains about 3 billion base...Ch. 12 - The mitotic cell divisions in the early embryo of...Ch. 12 - In an experiment published in the journal Cell in...Ch. 12 - a. What DNA sequences are found at the telomeres...Ch. 12 - Prob. 23PCh. 12 - a. In a fluorescent in situ hybridization FISH...Ch. 12 - If you are comparing the two telomeres in each...Ch. 12 - a. What DNA sequences are commonly found at human...Ch. 12 - On the graphs presented in Problem 21, no data is...Ch. 12 - Prob. 29PCh. 12 - Prob. 30PCh. 12 - In the 1920s, Barbara McClintock, later a Nobel...Ch. 12 - Give at least one example of a chromosomal...Ch. 12 - Cornelia de Lange syndrome CdLS is a rare human...Ch. 12 - a. Give at least three examples of types of...Ch. 12 - A number of yeast-derived elements were added to...Ch. 12 - Prob. 36PCh. 12 - The completely synthetic yeast chromosome Syn III...
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