Genetics: From Genes to Genomes, 5th edition
5th Edition
ISBN: 9780073525310
Author: Leland H. Hartwell, Michael L. Goldberg, Janice A. Fischer, Leroy Hood, Charles F. Aquadro
Publisher: McGraw-Hill Education
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Chapter 12, Problem 51P
Summary Introduction
a.
To determine:
The inference of two genes that are filled in dark purple color in K.waltii.
Introduction:
An organism cannot tolerate mutations in a gene. The mutations are essential for creating variations in the genes of an organism. The process of duplication provides two copies of the gene.
Summary Introduction
b.
To determine:
A hypothesis which explains the genesis of the part of S. cerevisiae genome that is given in the figure.
Introduction:
The process of evolution depends on the existence of variation in DNA sequences. The variants that enable the organism to survive normally in a particular environment will spread throughout the population.
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In yeast, LYS5, ADE1, and URA2 are genes required to synthesize lysine,
adenine and uracil, respectively. A MATa lys5 ADE1 URA2 haploid was mated
to a MATA LYS5 ade1 ura2 haploid to make a triply heterozygous diploid. This
diploid was put through meiosis, 100 tetrads were dissected and the spore
colonies transferred to medium lacking either lysine, adenine or uracil to
determine which spores were prototrophic or auxotrophic for those nutrients.
The following results were obtained:
LYS5-ADE1
ADE1-URA2
LYS5-URA2
PD
NPD
Ι
20
22
58
18
20
62
50
8
42
Based on this information, select the statements below that are TRUE.
Select 4 correct answer(s)
A) The LYS5 and URA2 genes are linked.
B)
The genotypes of the four spores in the ADE1-URA2 tetratypes is
ade1 ura2
ade1 URA2
ADE1 ura2
ADE1 URA2
C) The map distance between ADE1 and URA2 is 51 CM.
D) ADE1 and URA2 are likely located on the same chromosome.
E) The map distance between LYS5 and URA2 is 29 CM.
☐ F) LYS5 and ADE1 independently assort…
Discuss how ultra violet light works as a mutagen. This could include:
What is UV light and the Mutations commonly introduced by UV light? What are the Repair mechanisms in yeast that fix damage caused by UV light?
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For a haploid fungus, the starting point in the biosynthesis of the amino acid
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Enzyme A
Enzyme B
Enzyme Ç
Compound X
It is know that genes encoding enzymes A and C are on two different
chromosomes.
Compound Y
Compound Z-
Arginine
A mutant strain of genotype a (lacking only enzyme A) is crossed to a mutant strain
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O 100%
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25%
Chapter 12 Solutions
Genetics: From Genes to Genomes, 5th edition
Ch. 12 - For each of the terms in the left column, choose...Ch. 12 - Prob. 2PCh. 12 - For each of the following types of chromosomal...Ch. 12 - For the following types of chromosomal...Ch. 12 - One of the X chromosomes in a particular...Ch. 12 - Prob. 6PCh. 12 - Prob. 7PCh. 12 - Prob. 8PCh. 12 - Two wild-type fragments of human genomic DNA from...Ch. 12 - Indicate which of the four major classes of...
Ch. 12 - The recessive, X-linked z1 mutation of the...Ch. 12 - Genes a and b are 21 m.u. apart when mapped in...Ch. 12 - In the following group of figures, the pink lines...Ch. 12 - Three strains of Drosophila Bravo, X-ray, and...Ch. 12 - Prob. 15PCh. 12 - Suppose a haploid yeast strain carrying two...Ch. 12 - In the mating between two haploid yeast strains...Ch. 12 - During ascus formation in Neurospora, any...Ch. 12 - In the following figure, black and pink lines...Ch. 12 - In Drosophila, the gene for cinnabar eye color is...Ch. 12 - Semisterility in corn, as seen by unfilled ears...Ch. 12 - Prob. 22PCh. 12 - Prob. 23PCh. 12 - Prob. 24PCh. 12 - Duchenne muscular dystrophy DMD is caused by a...Ch. 12 - Explain how transposable elements can cause the...Ch. 12 - The Drosophila genome normally harbors about 40 P...Ch. 12 - Prob. 28PCh. 12 - Fred and Mary have a child named Bob. The genomic...Ch. 12 - Uniparental disomy is a rare phenomenon in which...Ch. 12 - Among adults with Turner syndrome, it has been...Ch. 12 - In Neurospora, his2 mutants require the amino acid...Ch. 12 - Human geneticists interested in the effects of...Ch. 12 - The incidence of Down syndrome will be very high...Ch. 12 - The Drosophila chromosome 4 is extremely small;...Ch. 12 - Down syndrome is usually caused by having a...Ch. 12 - Common red clover, Trifolium pratense, is a...Ch. 12 - The numbers of chromosomes in the somatic cells of...Ch. 12 - Prob. 39PCh. 12 - Somatic cells in organisms of a particular diploid...Ch. 12 - Prob. 41PCh. 12 - Prob. 42PCh. 12 - Chromosomes normally associate during meiosis I as...Ch. 12 - Using whole-genome sequencing, how could you...Ch. 12 - Prob. 45PCh. 12 - Prob. 46PCh. 12 - Seedless watermelons that you find in the...Ch. 12 - Prob. 48PCh. 12 - What characteristic property of translocations...Ch. 12 - In examining the genome of the rice Oryza sativa...Ch. 12 - Prob. 51PCh. 12 - Prob. 52PCh. 12 - The accompanying figure shows idiograms of human...
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