Life: The Science of Biology
11th Edition
ISBN: 9781319010164
Author: David E. Sadava, David M. Hillis, H. Craig Heller, Sally D. Hacker
Publisher: W. H. Freeman
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Chapter 13.3, Problem 4R
Summary Introduction
To review:
The dideoxycytidine drug and its interaction with the DNA molecule.
Introduction:
DNA is deoxyribonucleic acid and it is known to be a genetic material for all the organisms, expect viruses. Dideoxycytidine is a drug which is widely used to treat the viral infections. This drug interacts with the DNA and inhibits the synthesis of the DNA and hence it stops the growth of the virus.
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DNA in the form of a double helix must be associated with cations, usually Mg²+ . Why is this requirement the case?
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Life: The Science of Biology
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- There are four different type of nucleic acids which may be strung together to make DNA. These four nucleotides are called _________________________________, _______________________________, _______________________________ and ______________________. All four of these nucleic acids contain the same sugar and phosphate groups; where they differ is in their _________________ ______________arrow_forwardA nucleoside consists of an organic base, bound to ribose or deoxyribose. Draw the structure for deoxyguanosine, formed from guanine and deoxyribose.arrow_forwardIn the DNA structure, a purine molecule always binds with a pyrimidine molecule. How would you expect the structure to differ if Adenine forms base pairing with Guanine and Cytosine forms base pairing with Thymidine? Instead of A-T, G-C; can it be A-G, C-T? Justify your answer within five sentencesarrow_forward
- true or false Primary amines and keto groups of the nitrogen bases are involved in base-pairing in double stranded DNA.arrow_forwardA double-stranded molecule of B DNA contains 340 nucleotides. How many complete turns occur in this double helix?arrow_forwardHydrogen bonds are important in DNA replication and transcription. They are relatively weak chemical bonds. Why is this a desirable feature for DNA?arrow_forward
- All naturally occurring polysaccharides have one terminal residue, which contains a free anomeric carbon. Why do these polysaccharides not give a positive chemical test for a reducing sugar?Please explainarrow_forwardtrue or false: a nucleotide’s 5 end provides the energy to synthesize a new strand of DNA.arrow_forwardSketch a pyrimidine nucleotide subunit that would be found only in RNA. Circle and label the three components that make up this type of nucleotide. Explain what changes in the functional groups of this subunit would have to occur for it to be found in a DNA molecule.arrow_forward
- Which of the following descriptions best describes the composition of nucleotides? Group of answer choices A. a pentose sugar and a purine or pyrimidine B. a nitrogenous base, a phosphate group, and a pentose sugar C. a nitrogenous base and a pentose sugar D. a nitrogenous base and a phosphate group E. a phosphate group and an adenine or uracilarrow_forwardIn DNA polymer, one nucleotide joins with its neighboring nucleotide at 5' carbon. is it true or falsearrow_forwardA researcher is studying the effect of pH on a nucleic acid assuming it is DNA.She adds the nucleic acid in a tube labeled pH = 13. Sometime later when sheexamines the structure, she sees broken strands with cyclic structures formed involving phosphate group. a. (question) Do you agree that the nucleic acid is DNA? Why or why not?arrow_forward
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