Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 13.4, Problem 3COMQ
An enzyme known as _______attaches an amino acid to the _______of a tRNA, thereby producing _______.
a. aminoacyl-tRNA synthetase, anticodon, a charged tRNA
b. aminoacyl-tRNA synthetase, 3′ single-stranded region of the acceptor stem, a charged tRNA
c. polynucleotide phosphorylase, anticodon, a charged tRNA
d. polynucleotide phosphorylase, anticodon, an aminoacyl-tRNA
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The codon UUU in an mRNA molecule which results in phenylalanine being inserted as the protein is made. Which will be a characteristic of this codon?
a. The tRNA molecule that binds to the UUU codon must have an AAA anticodon. Nde ba e2?
b. UUU could code for both phenylalanine and alanine during translation.
c. The aminoacyl-tRNA synthetase for phenylalanine binds only the UUU codon.
d. UUU is probably only one of several codons that code for phenylalanine.
Which statement BEST DESCRIBES the tRNA structure?
A. Amino acids bind to the 5′ end of the tRNA molecule.
B. When a tRNA has an amino acid attached to it, it is considered to be a charged tRNA
C. Synthetases are not important to tRNA
D. Amino acids are linked to tRNAs with hydrogen bonds
A particular tRNA is mutated so that the amino acid attachment cannot bind with the aminoacyl-tRNA synthase. What happens when an mRNA transcript contains the codon for this tRNA?
A.
The tRNA will not bind to this codon.
B.
Translation stops and the protein is released.
C
The wrong tRNA is added to the protein chain.
D.
Translation stops and the protein remains bound to the ribosome.
Chapter 13 Solutions
Genetics: Analysis and Principles
Ch. 13.1 - Prob. 1COMQCh. 13.1 - 2. The reason why Beadle and Tatum observed four...Ch. 13.2 - What is the genetic code? a. The relationship...Ch. 13.2 - Prob. 2COMQCh. 13.2 - The fourth codon in an mRNA sequence is GGG, which...Ch. 13.2 - Prob. 4COMQCh. 13.3 - Prob. 2COMQCh. 13.4 - Prob. 1COMQCh. 13.4 - 2. The anticodon of a tRNA is located in the
a....Ch. 13.4 - An enzyme known as _______attaches an amino acid...
Ch. 13.5 - Each ribosomal subunit is composed of a. multiple...Ch. 13.5 - Prob. 2COMQCh. 13.6 - 1. During the initiation stage of translation in...Ch. 13.6 - The Kozak rules determine a. the choice of the...Ch. 13.6 - During the peptidyl transfer reaction, the...Ch. 13.6 - A release factor is referred to as a molecular...Ch. 13 - Prob. 1CONQCh. 13 - What does it mean when we say that the genetic...Ch. 13 - According to the adaptor hypothesis, is each of...Ch. 13 - Prob. 4CONQCh. 13 - Prob. 5CONQCh. 13 - 6. The wobble rules for tRNA-mRNA pairing are...Ch. 13 - Prob. 7CONQCh. 13 - Prob. 8CONQCh. 13 - Prob. 9CONQCh. 13 - If a tRNA has an anticodon sequence 3CCI5, what...Ch. 13 - Describe the anticodon of a single tRNA that could...Ch. 13 - Prob. 12CONQCh. 13 - Prob. 13CONQCh. 13 - 14. What is the role of aminoacyl-tRNA synthetase?...Ch. 13 - Prob. 15CONQCh. 13 - 16. Discuss the significance of modified bases...Ch. 13 - How and when does formylmethionine become attached...Ch. 13 - Prob. 18CONQCh. 13 - Prob. 19CONQCh. 13 - Prob. 20CONQCh. 13 - The term subunit can be used in a variety of ways....Ch. 13 - 22. Do the following events during bacterial...Ch. 13 - 23. What are the three stages of translation?...Ch. 13 - Prob. 24CONQCh. 13 - 25. For each of the following initiation factors,...Ch. 13 - Prob. 26CONQCh. 13 - 27. For each of the following sequences, rank them...Ch. 13 - Prob. 28CONQCh. 13 - Prob. 29CONQCh. 13 - Prob. 30CONQCh. 13 - Prob. 31CONQCh. 13 - In which of the ribosomal sites, the A site, P...Ch. 13 - Prob. 33CONQCh. 13 - Prob. 34CONQCh. 13 - Prob. 35CONQCh. 13 - Prob. 36CONQCh. 13 - Prob. 37CONQCh. 13 - 1. In the experiment of Figure 13.7, what would be...Ch. 13 - 2. Polypeptides can be translated in vitro. Would...Ch. 13 - Discuss how the elucidation of the structure of...Ch. 13 - Describe the structure of a polysome, which is...Ch. 13 - Prob. 5EQCh. 13 - 6. The technique of Western blotting is described...Ch. 13 - The protein known as tyrosinase is needed to make...Ch. 13 - Prob. 8EQCh. 13 - Discuss why you think the ribosomes need to...Ch. 13 - 2. Discuss and make a list of the similarities...Ch. 13 - 3. Which events during translation involve...
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- The peptide bond formation a. occurs when two tRNAs are located inside the P and A site in the ribosome b. occurs when the anticodon recognizes the codon c. occurs when two tRNAs come in close proximity in the cell d. occurs with the help of the tRNAase enzymearrow_forwardWhich of the following is not true? A.) A single activating enzyme can interact with all the tRNAs for its corresponding amino acid B.) The selectivity of the aminoacyl-tRNA sunthetases for their tRNA molecules is oftern called the second Genetic code C.) There are two major classes of aminoacyl-tRNA syntetases D.) Aminoacyl-tRNA synthetases link amino acids to tRNA molecules without the need for an energy sourcearrow_forwardWhich part of a tRNA molecule acts as an amino acid attachment site? a. the 5' end b. the 3' end c. the anticodon d. any of thesearrow_forward
- At least one nonsense suppressing tRNA is knownthat can suppress more than one type of nonsensecodon.a. What is the anticodon of such a suppressing tRNA?b. What stop codons would it suppress?c. Could this tRNA possibly also function as a missense suppressor?d. What are the amino acids most likely to be carriedby this suppressing tRNA?arrow_forwardA segment of DNA has the followimg sequence of bases.. 5'-ATGCAATGATATTGAAGCTTA-3' a) What sequence of bases would appear in mRNA transcribed from this segment? b) Assume the first base in this mRNA is the beginning of a codon. What order of amino acid would be translated into a polypeptide synthesized along this segment? c) Give anticodons for each tRNA associated with the translation in part (b)arrow_forwardDescribe the structural features that all tRNA molecules have in common.arrow_forward
- Which of the following would explain the formation of double-stranded loops in tRNA? A. complementary base pairing B. steric interactions between the aromatic rings of the purine bases C. electronic interactions between the negatively-charged phosphate groups D. change in the conformation of the rings of the sugarsarrow_forwardThere are 61 mRNA codons that specify an amino acid, but only 45 tRNAs. This is best explained by the fact that A. some tRNAs have anticodons that recognize two or more different codons. B. the rules for base pairing between the third base of a codon and tRNA are flexible. C. many codons are never used, so the tRNAs that recognize them are dispensable. D. A and B only E. A, B, and Carrow_forwardDetermine whether this statement is true or false: Aminoacyl-tRNA synthetase covalently links the amino acid to the 5’ end of the correct tRNA molecule.arrow_forward
- You are studying with a friend who says that the hydrogen-bonded portions of tRNA play no important role in its function. What is your reply?arrow_forwardIn the chain elongation of proteins, the new aminoacyl-tRNA bonds to? a.A site b.E site c.G site d.P sitearrow_forwardWhat is the significance (or function) of tRNA in protein synthesis? In other words, explain why tRNA is so important. How many different tRNA’s are there?arrow_forward
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