Chapter 15, Problem 57SA

Summary Introduction

To review:

The end product of the catabolism of the pyrimidine base thymine, the circumstances that lead to excess production of the same, and the reason it does not cause any illnesses, like gout.

Introduction:

Thymine is one of the nitrogenous bases of DNA (deoxyribonucleic acid). In animal cell, she catabolism of these pyrimidine bases occurs through dephosphorylation, deaminatio, nnd the cleavage of the glycosidic bond. The products of pyrimidine catabolism are β-alanine and β-minoisobutyrate. These are further degraded to acetyl CoA (coenzyme A) and succinyl CoA, respectively. Uric acid is the product of purine catabolism.