Biochemistry: The Molecular Basis of Life
6th Edition
ISBN: 9780190209896
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 15, Problem 25RQ
Summary Introduction
To review:
The number of ATP molecules (adenosine triphosphate) generated when NADH (reduced nicotinamide adenine dinucleotide) is oxidized in the mitochondria, and the net ATP requirement for urea synthesis.
Introduction:
In the mitochondria, all the ammonia molecules come together with the respiration byproduct carbon dioxide to form carbamoyl phosphate, which enters the urea cycle. The urea cycle requires energy in the form of ATP, and hence, is energetically expensive, but it occurs anyway in the body because it is necessary to eliminate toxic products from the body.
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What two major kinds of chemical reactions occur in the citric acid cycle, and how are these reactions indicated symbolically?
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Question 1: The overall process enabled by the glyoxylate cycle is:
(2acetyl-CoA) + (NAD+) + (2H2O) → (succinate) + (2CoA) + (NADH) + (2H+)
Dissect this process further by writing down all of the reactions that are actually involved in making one succinate from two acetyl-CoA units. Show chemical structure for all intermediates.
Chapter 15 Solutions
Biochemistry: The Molecular Basis of Life
Ch. 15 - Prob. 1QCh. 15 - Prob. 2QCh. 15 - Prob. 5QCh. 15 - Prob. 6QCh. 15 - Prob. 7QCh. 15 - Prob. 1RQCh. 15 - Prob. 2RQCh. 15 - Prob. 3RQCh. 15 - Prob. 4RQCh. 15 - Prob. 5RQ
Ch. 15 - Prob. 6RQCh. 15 - Prob. 7RQCh. 15 - Prob. 8RQCh. 15 - Prob. 9RQCh. 15 - Prob. 10RQCh. 15 - Prob. 11RQCh. 15 - Prob. 12RQCh. 15 - Prob. 13RQCh. 15 - Prob. 14RQCh. 15 - Prob. 15RQCh. 15 - Prob. 16RQCh. 15 - Prob. 17RQCh. 15 - Prob. 18RQCh. 15 - Prob. 19RQCh. 15 - Prob. 20RQCh. 15 - Prob. 21RQCh. 15 - Prob. 22RQCh. 15 - Prob. 23RQCh. 15 - Prob. 24RQCh. 15 - Prob. 25RQCh. 15 - Prob. 26RQCh. 15 - Prob. 27RQCh. 15 - Prob. 28RQCh. 15 - Prob. 29RQCh. 15 - Prob. 30RQCh. 15 - Prob. 31RQCh. 15 - Prob. 32RQCh. 15 - Prob. 33RQCh. 15 - Prob. 34RQCh. 15 - Prob. 35RQCh. 15 - Prob. 36RQCh. 15 - Prob. 37RQCh. 15 - Prob. 38RQCh. 15 - Prob. 39RQCh. 15 - Prob. 40RQCh. 15 - Prob. 41RQCh. 15 - Prob. 42RQCh. 15 - Prob. 43RQCh. 15 - Prob. 44RQCh. 15 - Prob. 45FBCh. 15 - Prob. 46FBCh. 15 - Prob. 47FBCh. 15 - Prob. 48FBCh. 15 - Prob. 49FBCh. 15 - Prob. 50FBCh. 15 - Prob. 51FBCh. 15 - Prob. 52FBCh. 15 - Prob. 53FBCh. 15 - Prob. 54FBCh. 15 - Prob. 55SACh. 15 - Prob. 56SACh. 15 - Prob. 57SACh. 15 - Prob. 58SACh. 15 - Prob. 59SACh. 15 - Prob. 60TQCh. 15 - Prob. 61TQCh. 15 - Prob. 62TQCh. 15 - Prob. 63TQCh. 15 - Prob. 64TQCh. 15 - Prob. 65TQCh. 15 - Prob. 66TQCh. 15 - Prob. 67TQCh. 15 - Prob. 68TQCh. 15 - Prob. 69TQCh. 15 - Prob. 71TQCh. 15 - Prob. 72TQCh. 15 - Prob. 73TQCh. 15 - Prob. 74TQ
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- What reaction glucoamylase catalyzes and why?arrow_forwardWhich reaction in the citric acid cycle is most analogous to the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate? What kind of enzymebound intermediate is formed in both reactions?arrow_forwardGiven the question as what os the role of L- carnitine in fatty acid metabolism, what is the correct answer?arrow_forward
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- Why is the Krebs cycle considered part of aerobic metabolism, even though O2 does not appear in any of its catalytic reaction?arrow_forwardAll coenzymes are cofactors, but not all cofactors are coenzymes. Explain this statement.arrow_forwardWhere does aspartate enter the urea cycle and what compound does it eventually leave as? What metabolic cycle does this compound then enter?arrow_forward
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