Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 15.2, Problem 1COMQ
A chromatin-remodeling complex may
a. change the locations of nucleosomes.
b. evict nucleosomes from DNA.
c. replace standard histones with histone variants.
d. do all of the above.
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Chromatin remodeling is affected by two processes, DNA methylation and a. base substitution b. histone covalent modifications c. ultraviolet radiation d. transcription factor binding
Which of the following statements is NOT true about chromatin architecture?
A. The histone tails on heterochromatin are deacetylated
B. Heterochromatin is heavily methylated
C. Euchromatin is more likely to contain genes that are expressed at that time
D. Euchromatin is heavily methylated
Insulators may exert their effect by
a. acting as a barrier to changes in chromatin structure.
b. blocking the effects of neighboring enhancers.
c. doing both a and b.
d. none of the above.
Chapter 15 Solutions
Genetics: Analysis and Principles
Ch. 15.1 - 1. Combinatorial control refers to the phenomenon...Ch. 15.1 - 2. A regulatory transcription factor protein...Ch. 15.1 - 3. A bidirectional enhancer has the following...Ch. 15.1 - 4. Regulatory transcription factors can be...Ch. 15.2 - 1. A chromatin-remodeling complex may
a. change...Ch. 15.2 - Prob. 2COMQCh. 15.2 - 3. Which of the following characteristics is...Ch. 15.2 - 4. Transcriptional activation of eukaryotic genes...Ch. 15.3 - How can methylation affect transcription? a. It...Ch. 15.3 - 2. The process in which completely unmethylated...
Ch. 15.4 - Prob. 1COMQCh. 15.5 - The overall goal of the ENCODE Project is a. to...Ch. 15.6 - The binding of iron regulatory protein (IRP) to...Ch. 15 - Discuss the common points of control in eukaryotic...Ch. 15 - 2. Discuss the structure and function of...Ch. 15 - 3. What is meant by the term transcription factor...Ch. 15 - What are the functions of transcriptional...Ch. 15 - 5. Is each of the following statements true or...Ch. 15 - 6. Transcription factors usually contain one or...Ch. 15 - Prob. 7CONQCh. 15 - Prob. 8CONQCh. 15 - 9. Let’s suppose a mutation in the glucocorticoid...Ch. 15 - Prob. 10CONQCh. 15 - Prob. 11CONQCh. 15 - Prob. 12CONQCh. 15 - 13. Transcription factors such as the...Ch. 15 - An enhancer, located upstream from a gene, has the...Ch. 15 - 15. The DNA-binding domain of each CREB protein...Ch. 15 - The gene that encodes the enzyme called tyrosine...Ch. 15 - Prob. 17CONQCh. 15 - 18. What is a histone variant?
Ch. 15 - Prob. 19CONQCh. 15 - 20. What is meant by the term histone code? With...Ch. 15 - Prob. 21CONQCh. 15 - Histones are thought to be displaced as RNA...Ch. 15 - 23. What is an insulator? Describe two different...Ch. 15 - 24. What is DNA methylation? When we say that DNA...Ch. 15 - Lets suppose that a vertebrate organism carries a...Ch. 15 - 26. What is a CpG island? Where would you expect...Ch. 15 - Describe how the binding of iron regulatory...Ch. 15 - 1. Briefly describe the method of chromatin...Ch. 15 - Researchers can isolate a sample of cells, such as...Ch. 15 - Prob. 3EQCh. 15 - Prob. 4EQCh. 15 - Prob. 5EQCh. 15 - 6. As described in Chapter 21, an electrophoretic...Ch. 15 - Prob. 7EQCh. 15 - 1. Explain how DNA methylation could be used to...Ch. 15 - 2. Enhancers can occur almost anywhere in DNA and...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Histones form more accessible chromatin because of Select one: a. Reduced electrostatic attraction between the histone and the negatively charged DNA backbone b. Increased electrostatic attraction between the histone and the negatively charged DNA backbone c. Reduced covalent bonding between the histone and the negatively charged DNA backbone d. Increased covalent bonding between the histone and the negatively charged DNA backbonearrow_forward_____ is the combination of a seat, elation, another modifications to the histones that allow for changes in DNA winding and unwinding a. Epigentics b. Histone code c. Heterochromatin d. Post translational modificationsarrow_forwardThe conversion of euchromatin into heterochromatin involvesa. the formation of more nucleosomes.b. the formation of less nucleosomes.c. a greater compaction of loop domains.d. a lesser compaction of loop domains.e. both a and c.arrow_forward
- Which of the following decrease gene activity? a. acetylation of histone proteins b. methylation of histone proteins c. methylation of cytosines in DNA d. all the above decrease gene activityarrow_forwardWhich of these is NOT true of nucleosomes? A. Some post-translational modifications to histone proteins serve as binding sites for transcription factors. B. The position of nucleosomes is fixed on the genome and can not be changed. C. The position and post-translational modifications of histones can be inherited through mitosis. D. The binding between DNA and histone proteins can be disrupted by post-translational modifications.arrow_forwardDescribe the mechanism by which histone modifications are established after DNA replication and cell division. What are some things that could go wrong if modifications can't be maintained? Think about what histone modifications do to DNA and why cells maintain parts of their chromosome as heterochromatin.arrow_forward
- Describe how reversible chemical changes to DNA and histones are linked to chromatin modification.arrow_forwardWhich of the following statements about histones is true?a. They are proteins whose sequence is highly conserved in all eukaryotes.b. They are the building blocks of nucleosomes.c. a and b are correct.d. None of the above are correct.arrow_forwardWhich of the following is associated with active chromatin? Check all that apply. A. Centromeres B. heterochromatin C. histone acetylation D. Polytene puffs E. metaphase chromasomes F. transcription of machineryarrow_forward
- Heterochromatin consists of a) region of euchromatin devoid of histones. b) an AT-rich region occurs every 200 base pairs. c) decondensed, transcriptionally active chromatin. d) highly condensed, transcriptionally inactive chromatinarrow_forwardResearch has shown that more mutations accumulate in regions of a chromosome that consist of compact chromatin, such as heterochromatin. Offer an explanation for why mutation rates would be higher where chromatin is more compact.arrow_forwardAccording to the histone code hypothesis, the pattern of histone modifications acts like a language that a. influences chromatin structure. b. promotes transcriptional termination. c. inhibits the elongation of RNA polymerase. d. does all of the above.arrow_forward
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