Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 15.2, Problem 3COMQ
Which of the following characteristics is typical of a eukaryotic gene that can be transcribed?
a. The core promoter is wrapped around a nucleosome.
b. The core promoter is found in a nucleosome-free region.
c. The terminator is wrapped around a nucleosome.
d. None of the above characteristics is typical of such a gene.
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Students have asked these similar questions
Which of the following statements best describes the promoter of a protein-coding gene?
A.
The promoter is a protein that recruits RNA polymerase.
B.
The promoter is part of the RNA molecule itself.
C.
The promoter is a site found on RNA polymerase.
D.
The promoter contains the AUG start codon.
E.
The promoter is a nontranscribed region of a gene.
If a mutation occurred in a control element sequence associated with a particular gene, which of the following would be a likely consequence of this?
A. This mutation is not likely to affect the expression of the associated gene, because RNA polymerase does not bind to control elements.
B. This will likely affect the expression of the associated gene because it will loosen the coiling of chromatin at this site.
C. The expression of the associated gene will be affected because this change will result in a nonsense mutation.
D. This mutation is not likely to affect the expression of the associated gene, since control elements are noncoding sequences.
E. The associated gene's expression would likely be affected, since this mutation would change the ability of at least one transcription factor to bind.
a) What is a gene promoter? b) What proteins bind to a promoter? c) What do those proteins do to control gene expression?
Chapter 15 Solutions
Genetics: Analysis and Principles
Ch. 15.1 - 1. Combinatorial control refers to the phenomenon...Ch. 15.1 - 2. A regulatory transcription factor protein...Ch. 15.1 - 3. A bidirectional enhancer has the following...Ch. 15.1 - 4. Regulatory transcription factors can be...Ch. 15.2 - 1. A chromatin-remodeling complex may
a. change...Ch. 15.2 - Prob. 2COMQCh. 15.2 - 3. Which of the following characteristics is...Ch. 15.2 - 4. Transcriptional activation of eukaryotic genes...Ch. 15.3 - How can methylation affect transcription? a. It...Ch. 15.3 - 2. The process in which completely unmethylated...
Ch. 15.4 - Prob. 1COMQCh. 15.5 - The overall goal of the ENCODE Project is a. to...Ch. 15.6 - The binding of iron regulatory protein (IRP) to...Ch. 15 - Discuss the common points of control in eukaryotic...Ch. 15 - 2. Discuss the structure and function of...Ch. 15 - 3. What is meant by the term transcription factor...Ch. 15 - What are the functions of transcriptional...Ch. 15 - 5. Is each of the following statements true or...Ch. 15 - 6. Transcription factors usually contain one or...Ch. 15 - Prob. 7CONQCh. 15 - Prob. 8CONQCh. 15 - 9. Let’s suppose a mutation in the glucocorticoid...Ch. 15 - Prob. 10CONQCh. 15 - Prob. 11CONQCh. 15 - Prob. 12CONQCh. 15 - 13. Transcription factors such as the...Ch. 15 - An enhancer, located upstream from a gene, has the...Ch. 15 - 15. The DNA-binding domain of each CREB protein...Ch. 15 - The gene that encodes the enzyme called tyrosine...Ch. 15 - Prob. 17CONQCh. 15 - 18. What is a histone variant?
Ch. 15 - Prob. 19CONQCh. 15 - 20. What is meant by the term histone code? With...Ch. 15 - Prob. 21CONQCh. 15 - Histones are thought to be displaced as RNA...Ch. 15 - 23. What is an insulator? Describe two different...Ch. 15 - 24. What is DNA methylation? When we say that DNA...Ch. 15 - Lets suppose that a vertebrate organism carries a...Ch. 15 - 26. What is a CpG island? Where would you expect...Ch. 15 - Describe how the binding of iron regulatory...Ch. 15 - 1. Briefly describe the method of chromatin...Ch. 15 - Researchers can isolate a sample of cells, such as...Ch. 15 - Prob. 3EQCh. 15 - Prob. 4EQCh. 15 - Prob. 5EQCh. 15 - 6. As described in Chapter 21, an electrophoretic...Ch. 15 - Prob. 7EQCh. 15 - 1. Explain how DNA methylation could be used to...Ch. 15 - 2. Enhancers can occur almost anywhere in DNA and...
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- A certain Drosophila protein-encoding gene has one intron. If a large sample of null alleles of this gene is examined, will any of the mutant sites be expecteda. in the exons?b. in the intron?c. in the promoter?d. in the intron–exon boundary?arrow_forwardIf a mutation deletes the promoter in a eukrayotic gene, which of the following most accurately describes its consequence? A. There will be no mRNA or polypeptide made. B. The mRNA will be made but no polypeptide is made. C. The mRNA will not be processed properly. D. Nothing will happen. It is a silent mutation.arrow_forwardWhich of the following is true of transcription factors? A)The same transcription factors are found in all cell types. B)They can increase or decrease gene expression. C)They are a type of cis-acting element. D)They bind only to promoters.arrow_forward
- In the given below characteristics which are typical of a eukaryotic gene that can be transcribed? 1. The core promoter is wrapped around a nucleosome. 2. The core promoter is found in a nucleosome-free region. 3. The terminator is wrapped around a nucleosome. 4. None of the above characteristics is typical of such a gene.arrow_forwardWhich of the following best represents the central dogma of geneexpression?a. During transcription, DNA codes for polypeptides.b. During transcription, DNA codes for mRNA, which codes forpolypeptides during translation.c. During translation, DNA codes for mRNA, which codes forpolypeptides during transcription.d. none of the abovearrow_forwardIf a gene sequence is more tightly coiled around histones, then which of the following is the most likely consequence? A) This gene is more likely to undergo mutation as it is being expressed B) This gene is unlikely to be transcribed while in this conformation C) This gene will be transcribed often while in this conformation D) This gene will be translated more efficiently .arrow_forward
- Sickle cell disease is caused by a substitution in the beta globin gene. As a result, one amino acid is different in the mutant protein. Which of the following region is likely to be affected in the sickle cell allele? A. The promoter region B. The 5' UTR region C. The coding region D. The 3' UTRarrow_forwardIf you want to express a eukaryotic gene in a bacterial cell, you ned to (select all that apply): a.) add a bacterial promoter in front of the gene b.) remove introns from the gene c.) add a polyA tail sequence d.) add eukaryotic tRNAsarrow_forwardWhy can the transcriptome not be used to predict the proteome with complete accuracy? a. It cannot be sequenced like the genome can be. b. The transcriptome is too dynamic to be used to make predictions. c. Not all genes are transcribed. d. Many transcripts are alternatively spliced to produce different proteins.arrow_forward
- Which sequence is most likely to be found in a promoter? a) CGGTGTATATCGTAC b) GTACAGTCATCCCGT c) AAATCTACTACGATT d) GGGTTGGGTTGGGTTarrow_forwardf you made a change in the promoter sequence in the DNA that inactivates the promoter, what would happen at the RNA level? A-Nothing, because the RNA would be made as usual B-Transcription factors would be unable to bind and the RNA polymerase would not be recruited to the DNA, so no RNA would be made. C-The mutation of the DNA would be carried through to the RNA sequence. D-The DNA helicase would not be able to recognize and bind the DNA, so the RNA would not be made. EXPLAIN WHY THE ANSWER YOU CHOOSE IS CORRECTarrow_forwardWhat are two reasons that a eukaryotic gene (e.g. Green Fluorescent Protein in jellyfish) will not be expressed if it is inserted into a bacterial genome with no alterations? a. Bacterial genes do not contain introns b. Bacterial promoters have different consensus sequences than eukaryotic ones c. Transcription of this gene is affected by the simultaneous processes of transcription and translation d.arrow_forward
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