The reason why two steps of pyruvate oxidative decarboxylation, do not involves any of the three carbons of pyruvate, but are necessary for the operation of PDH complex. Introduction: Pyruvate is obtained from glycolysis and then transported into matrix of mitochondria through mitochondrial pyruvate carrier. In mitochondrial matrix, an enzyme called pyruvate dehydrogenase complex (PDH) converts the pyruvate into acetyl-CoA. Three types of enzyme are involved in the composition of PDH. These enzymes are E 1 (pyruvate dehydrogenase), E 2 (dihydrolipoyl transacetylase), and E 3 (dihydrolipoyl dehydrogenase). These enzymes are found in mitochondria of eukaryotes and cytosol of bacteria.

Question

Want to see the full answer?

Answer 1

Question

Chapter 16, Problem 33P

Summary Introduction

To explain: The reason why two steps of pyruvate oxidative decarboxylation, do not involves any of the three carbons of pyruvate, but are necessary for the operation of PDH complex.

Introduction: Pyruvate is obtained from glycolysis and then transported into matrix of mitochondria through mitochondrial pyruvate carrier. In mitochondrial matrix, an enzyme called pyruvate dehydrogenase complex (PDH) converts the pyruvate into acetyl-CoA.

Three types of enzyme are involved in the composition of PDH. These enzymes are E1 (pyruvate dehydrogenase), E2 (dihydrolipoyl transacetylase), and E3 (dihydrolipoyl dehydrogenase). These enzymes are found in mitochondria of eukaryotes and cytosol of bacteria.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 2

Question

Chapter 16, Problem 33P

Summary Introduction

To explain: The reason why two steps of pyruvate oxidative decarboxylation, do not involves any of the three carbons of pyruvate, but are necessary for the operation of PDH complex.

Introduction: Pyruvate is obtained from glycolysis and then transported into matrix of mitochondria through mitochondrial pyruvate carrier. In mitochondrial matrix, an enzyme called pyruvate dehydrogenase complex (PDH) converts the pyruvate into acetyl-CoA.

Three types of enzyme are involved in the composition of PDH. These enzymes are E1 (pyruvate dehydrogenase), E2 (dihydrolipoyl transacetylase), and E3 (dihydrolipoyl dehydrogenase). These enzymes are found in mitochondria of eukaryotes and cytosol of bacteria.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 3

Question

Chapter 16, Problem 33P

Summary Introduction

To explain: The reason why two steps of pyruvate oxidative decarboxylation, do not involves any of the three carbons of pyruvate, but are necessary for the operation of PDH complex.

Introduction: Pyruvate is obtained from glycolysis and then transported into matrix of mitochondria through mitochondrial pyruvate carrier. In mitochondrial matrix, an enzyme called pyruvate dehydrogenase complex (PDH) converts the pyruvate into acetyl-CoA.

Three types of enzyme are involved in the composition of PDH. These enzymes are E1 (pyruvate dehydrogenase), E2 (dihydrolipoyl transacetylase), and E3 (dihydrolipoyl dehydrogenase). These enzymes are found in mitochondria of eukaryotes and cytosol of bacteria.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Chapter 16, Problem 33P

Summary Introduction

To explain: The reason why two steps of pyruvate oxidative decarboxylation, do not involves any of the three carbons of pyruvate, but are necessary for the operation of PDH complex.

Introduction: Pyruvate is obtained from glycolysis and then transported into matrix of mitochondria through mitochondrial pyruvate carrier. In mitochondrial matrix, an enzyme called pyruvate dehydrogenase complex (PDH) converts the pyruvate into acetyl-CoA.

Three types of enzyme are involved in the composition of PDH. These enzymes are E1 (pyruvate dehydrogenase), E2 (dihydrolipoyl transacetylase), and E3 (dihydrolipoyl dehydrogenase). These enzymes are found in mitochondria of eukaryotes and cytosol of bacteria.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 5

Chapter 16, Problem 33P

Summary Introduction

To explain: The reason why two steps of pyruvate oxidative decarboxylation, do not involves any of the three carbons of pyruvate, but are necessary for the operation of PDH complex.

Introduction: Pyruvate is obtained from glycolysis and then transported into matrix of mitochondria through mitochondrial pyruvate carrier. In mitochondrial matrix, an enzyme called pyruvate dehydrogenase complex (PDH) converts the pyruvate into acetyl-CoA.

Three types of enzyme are involved in the composition of PDH. These enzymes are E1 (pyruvate dehydrogenase), E2 (dihydrolipoyl transacetylase), and E3 (dihydrolipoyl dehydrogenase). These enzymes are found in mitochondria of eukaryotes and cytosol of bacteria.

Answer 6

Chapter 16, Problem 33P

Summary Introduction

To explain: The reason why two steps of pyruvate oxidative decarboxylation, do not involves any of the three carbons of pyruvate, but are necessary for the operation of PDH complex.

Introduction: Pyruvate is obtained from glycolysis and then transported into matrix of mitochondria through mitochondrial pyruvate carrier. In mitochondrial matrix, an enzyme called pyruvate dehydrogenase complex (PDH) converts the pyruvate into acetyl-CoA.

Three types of enzyme are involved in the composition of PDH. These enzymes are E1 (pyruvate dehydrogenase), E2 (dihydrolipoyl transacetylase), and E3 (dihydrolipoyl dehydrogenase). These enzymes are found in mitochondria of eukaryotes and cytosol of bacteria.

Answer 7

Chapter 16, Problem 33P

Summary Introduction

To explain: The reason why two steps of pyruvate oxidative decarboxylation, do not involves any of the three carbons of pyruvate, but are necessary for the operation of PDH complex.

Introduction: Pyruvate is obtained from glycolysis and then transported into matrix of mitochondria through mitochondrial pyruvate carrier. In mitochondrial matrix, an enzyme called pyruvate dehydrogenase complex (PDH) converts the pyruvate into acetyl-CoA.

Three types of enzyme are involved in the composition of PDH. These enzymes are E1 (pyruvate dehydrogenase), E2 (dihydrolipoyl transacetylase), and E3 (dihydrolipoyl dehydrogenase). These enzymes are found in mitochondria of eukaryotes and cytosol of bacteria.

Answer 8

Expert Solution & Answer

Answer 9

Expert Solution & Answer

Answer 10

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 11

Ch. 16 - Prob. 1P Ch. 16 - Prob. 2P Ch. 16 - Prob. 3P Ch. 16 - Prob. 4P Ch. 16 - Prob. 5P Ch. 16 - Prob. 6P Ch. 16 - Prob. 7P Ch. 16 - Prob. 8P Ch. 16 - Prob. 9P Ch. 16 - Prob. 10P

Concept explainers

Videos

Want to see the full answer?

Chapter 16 Solutions