Study Guide for Campbell Biology
Study Guide for Campbell Biology
11th Edition
ISBN: 9780134443775
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Jane B. Reece, Martha R. Taylor, Michael A. Pollock
Publisher: PEARSON
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Chapter 17, Problem 16TYK
Summary Introduction

Introduction: The genetic information of DNA is based on the nucleotide base sequences. These sequences are transcribed into mRNA triplets and are called codons. After transcription, mRNA sequences are read by tRNA in the ribosome to synthesize polypeptide, and the process is known as translation. tRNA molecules have an anticodon that pairs with its complementary codon during translation. As a result, the codon-specific amino acid comes through the other end of the tRNA. These amino acids form a polypeptide chain.

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Consider the following tRNAs, where the numbered forms represent the amino acids associated with them, answer briefly: PICTURE Question 1: The numbering indicates the order in which these tRNAs are recruited to the A site of the ribosome. Write the sequence of the mRNA being translated in the 5' - 3' direction Question 2: What is the amino acid sequence of the produced polypeptide? Question 3: Researchers discover that a mutation is in the anticodon of the gene encoding the proline tRNA of an individual. The anticodon sequence is normally 3' GGA 5', but in this individual the anticodon sequence is 3' GGG 5'. It appears that this individual suffers no adverse consequences. How can this be? (2 response items)
What is the significance (or function) of tRNA in protein synthesis? In other words, explain why tRNA is so important. How many different tRNA’s are there?
Is this diagram of tRNA technically incorrect? Shouldn't it be 3' on the left and 5' on the right for the tRNA such that the 5' to 3' codon can match with the antiparallel 3' to 5' anticodon?
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