Interpretation:
From the given molecules, the nucleophiles that will add reversibly and irreversibly to a polar
Concept introduction:
A polar
Nucleophilic addition tends to be irreversible if the negative charge that develops in the adduct is significantly better stabilized than it is in the nucleophile. This occurs in the nucleophile that has the negative charge located on a carbon or hydrogen atom, and the negative charge is not stabilized by resonance or inductive effects. Therefore, nucleophilic addition to a carbonyl carbon tends to be irreversible when it involves a very strong
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ORGANIC CHEMISTRY E-BOOK W/SMARTWORK5
- Consider the following groups of compounds. In each series circke the weaker (poorer) nucleophile. Please explain why.arrow_forwardWhich of the following reactions take place more rapidly when the concentration of the nucleophile is increasedarrow_forwardWhich of the following will react faster and whyarrow_forward
- Draw the curved electron pushing arrow for the following reaction or mechanistic steps. Be sure to account for all bond-breaking and bond-making stepsarrow_forwardCompare the following pairs of molecules and determine which one is the stronger nucleophilearrow_forwardMajor product and mechanism for this?arrow_forward
- Organic Chemistry: A Guided InquiryChemistryISBN:9780618974122Author:Andrei StraumanisPublisher:Cengage Learning