CAMPBELL BIOLOGY IN FOCUS-MOD.MASTERING
3rd Edition
ISBN: 9780135191811
Author: Urry
Publisher: PEARSON
expand_more
expand_more
format_list_bulleted
Concept explainers
Videos
Textbook Question
Chapter 18, Problem 5TYU
SCIENTIFIC INQUIRY
The scientists mapping human SNPs noticed that groups of SNPs tended to be inherited together. In blocks known as "haplotypes." ranging from 5.000 to 200,000 base pairs. There are only four or five commonly occurring combinations of SNPs per haplotype. Integrating what you've learned throughout this chapter and this unit, propose an explanation for this observation.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
Human Genome ProjectIn 2003, the Human Genome Project was successfully completed, determining the exact sequence of the entire human genome, which is made up of 3 billion nucleotide base pairs. The data generated from the Human Genome Project is freely available online to anyone. Many researches and innovations stemmed from the HGP, allowing the identifications of 1 800 disease genes. Many of the corporations using the results from the HGP are privately funded, and research is being done for profit even though the HGP results are provided freely.Identify one advantage and one disadvantage of corporate funding and patenting genetic research results.
Please answer all parts along with the reason. I'll definitely give a like. Thank you in advance!
1A) From the cross Ab/aB x ab/ab, what is the recombination frequency if the progeny numbers are 17 AB/ab, 72 Ab/ab, 68 aB/ab, and 21 ab/ab?
1B)In human gene mapping, a LOD score is calculated to see if a gene causing a rare disease is linked to a known SNP. The LOD score is -4. This means that
1C) A three-point testcross is used to determine the order of three linked genes. The following crossover progeny result: single crossovers, double crossovers, and no crossovers. To determine the order, the no-crossover progeny must be compared to what other class of progeny?
. Figure 18-14 presents haplotype data for the G6PD genein a worldwide sample of people.a. Draw a haplotype network for these haplotypes.Label the branches on which each SNP occurs.b. Which of the haplotypes has the most connectionsto other haplotypes?c. On what continents is this haplotype found?d. Counting the number of SNPs along the branchesof your network, how many differences are therebetween haplotypes 1 and 12?
Chapter 18 Solutions
CAMPBELL BIOLOGY IN FOCUS-MOD.MASTERING
Ch. 18.1 - Prob. 1CCCh. 18.2 - Prob. 1CCCh. 18.2 - Explain the advantage of the systems biology...Ch. 18.2 - Prob. 3CCCh. 18.3 - The best estimate is that the human genome...Ch. 18.3 - Prob. 2CCCh. 18.3 - Prob. 3CCCh. 18.4 - Discuss the characteristics of mammalian genomes...Ch. 18.4 - Which of the three mechanisms described in Figures...Ch. 18.4 - Prob. 3CC
Ch. 18.5 - Describe three examples of errors in cellular...Ch. 18.5 - Prob. 2CCCh. 18.5 - Prob. 3CCCh. 18.6 - Would you expect the genome of the macaque (a...Ch. 18.6 - Prob. 2CCCh. 18 - Prob. 1TYUCh. 18 - Prob. 2TYUCh. 18 - Two eukaryotic proteins have one domain in common...Ch. 18 - DRAW IT Comparing amino acid sequences of similar...Ch. 18 - SCIENTIFIC INQUIRY The scientists mapping human...Ch. 18 - FOCUS ON EVOLUTION Genes important in the...Ch. 18 - FOCUS ON INFORMATION The continuity of life is...Ch. 18 - SYNTHESIZE YOUR KNOWLEDGE Insects have three...
Additional Science Textbook Solutions
Find more solutions based on key concepts
Jellyfish Lake, located on the Pacific island of Palau, is home to millions of jellyfish. Many years ago, sea l...
BIOLOGY:THE ESSENTIALS (LL) W/CONNECT
11. In the early 1800s, French naturalist Jean Baptiste Lamarck suggested that the best explanation for the rel...
Campbell Biology: Concepts & Connections (8th Edition)
2. Why is it that the range of resting blood pressures of humans is best represented by a bell-shaped curve co...
Human Biology: Concepts and Current Issues (8th Edition)
Describe Mendels conclusions about how traits are passed from generation to generation.
Concepts of Genetics (12th Edition)
What were the major microbiological interests of Martinus Beijerinck and Sergei Winogradsky? It can be said tha...
Brock Biology of Microorganisms (14th Edition)
Sea turtles have disappeared from many regions, and one way of trying to save them is to reintroduce them to ar...
Marine Biology (Botany, Zoology, Ecology and Evolution)
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- You learned in the chapter that an STR locus is a locus where alleles differ in the number of copies of a short, tandemly repeated DNA sequence. PCR is used to determine the number of alleles present, as shown by the size of the DNA fragment amplified. In the Figure below are the results of PCR analysis for STR alleles at a locus where the repeat unit length is 9 bp, and alleles are known that have 5 to 11 copies of the repeat. Given the STR alleles present in the adults, state whether each of the four juveniles could or could not be an off-spring of those two adults. Explain your answers.arrow_forward. Use the following sequence data to assign haplotypes and build a haplotype network for a 200 bp variable region that is sequenced from eight individuals. Polymorphic nucleotide positions are shown. Δ is a 1 bp deletion. Explain the logic supporting the network. If there are different nucleotide changes at one position, indicate the different changes on your network. Individual 24 56 92 119 146 172 haplotype 1 A C A T G G A 2 T C Δ C G G 3 A G A T A T 4 A G A T G T 5 A C Δ C G G 6 A G A T G G 7 A G A T A T 8 C C Δ C G Garrow_forwardWhen comparing evolutionary similarities between different genes within a gene family, it is usually more straightforward to compare genes by using the protein sequences of gene products rather than DNA sequences of the genes themselves. Explain why this is the case. (Cover 4 points)arrow_forward
- Concept 23. A gene is a discrete sequence of DNA nucleotides. This concept describes the discovery of the DNA sequencing technique that made modern biology and bioinformatics possible. The method was later used to sequence the human genome and genomes of many other organisms. This led to the accumulation of great numbers of nucleotide and protein sequences in the numerous databases. The concept 23 web page is here: http://www.dnaftb.org/23/ After reading the Concept page, answer the following questions. What was the Mendel’s definition of a gene? How was it different from the definition by Beadle and Tatum? Describe proteins based on the early sequencing efforts. What was the definition of a protein coding gene based on the genetic code? What are the beginning and ending codons of the gene’s protein coding sequence? What is the name of the method that makes use of a “defective” DNA nucleotide? After reviewing the Animation pages, answer the following…arrow_forwardTake a look at question 3 in More Genetic TIPS. Let’s suppose amale is heterozygous for two polymorphic sequence-tagged sites.STS-1 exists in two sizes: 211 bp and 289 bp. STS-2 also exists intwo sizes: 115 bp and 422 bp. A sample of sperm was collectedfrom this man, and individual sperm were placed into 30 separatetubes. Into each of the 30 tubes were added the primers that amplifySTS-1 and STS-2, and then the samples were subjected toPCR. The following results were obtained:arrow_forwardScientists have estimated that there may be as many as . . or more different human proteins, all coded by . .protein-coding genes O 1: 500,000 & II 20,000 O 1: 20,000 & II: 500,000 O 1: 30,000 & II: 50,000 O 1: 50,000 & II: 30,000arrow_forward
- hello i need help with this DNA sometimes has chemicalgroups attached, called methyl groups, that affect geneexpression. Suppose that, during each hour, first a fractionm of unmethylated locations on the DNA become methylated,and then a fraction u of methylated locations become unmethylated. Find a recursion for the fraction f of theDNA molecule that is methylated.arrow_forwardUnanswered As a hobby you propagate a population of worms. You notice that one worm is now clear instead of being tan. You trace down the mutation and discover that it is a single basepair deletion in a pigmentation gene. Explain how a single basepair deletion could result in a drastic mutant phenotype. Your answer Write your response here... ion onarrow_forwardDescribe the 3 processes of central dogma of molecular biology. Share your thoughts on their significance in the transmission of traits(not more than 100 words).arrow_forward
- Explain in your own words what a SNP is.arrow_forwardThe technique of fluorescence in situ hybridization (FISH) is described. This is another method for examining sequence complexity within a genome. In this method, a DNA sequence, such as a particular gene sequence, can be detected within an intact chromosome by using a DNA probe that is complementary to the sequence.For example, let’s consider the β-globin gene, which isfound on human chromosome 11. A probe complementary to theβ-globin gene binds to that gene and shows up as a brightly colored spot on human chromosome 11. In this way, researchers can detectwhere the β-globin gene is located within a set of chromosomes. Becausethe β-globin gene is unique and because human cells are diploid(i.e., have two copies of each chromosome), a FISH experimentshows two bright spots per cell; the probe binds to each copy ofchromosome 11. What would you expect to see if you used thefollowing types of probes?A. A probe complementary to the Alu sequenceB. A probe complementary to a tandem array near…arrow_forwardSuppose a 10-year old patient has come to your office with a very rare disease. One so rare that only 100 people for the past 100 years have been diagnosed and nobody knows the gene or genes that are mutated in this disease. Describe the gene sequencing toold you would use to identify the mutated gene or genes in this hypothetical disease.arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Biology: The Dynamic Science (MindTap Course List)BiologyISBN:9781305389892Author:Peter J. Russell, Paul E. Hertz, Beverly McMillanPublisher:Cengage Learning
Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage Learning
Biology: The Dynamic Science (MindTap Course List)
Biology
ISBN:9781305389892
Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:Cengage Learning
Human Heredity: Principles and Issues (MindTap Co...
Biology
ISBN:9781305251052
Author:Michael Cummings
Publisher:Cengage Learning
Genome Annotation, Sequence Conventions and Reading Frames; Author: Loren Launen;https://www.youtube.com/watch?v=MWvYgGyqVys;License: Standard Youtube License