WORLD OF CELL+MASTERING ACCESS >CUSTOM
WORLD OF CELL+MASTERING ACCESS >CUSTOM
9th Edition
ISBN: 9781323445044
Author: Hardin
Publisher: PEARSON C
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Chapter 19, Problem 19.2PS

Tracking a Series of Mutations. The following diagram shows the amino acids that result from mutations in the codon for a particular amino acid in a bacterial polypeptide:

Chapter 19, Problem 19.2PS, Tracking a Series of Mutations. The following diagram shows the amino acids that result from     (19-2)

Assume that each arrow denotes a single base-pair substitution in the bacterial DNA.

  1. (a) Referring to the genetic code table in Figure 18-10, determine the most likely codons for each of the amino acids and the stop signal in the diagram.
  2. (b) Starting with a population of mutant cells carrying the nonsense mutation, another mutant is isolated in which the premature stop signal is suppressed. Assuming wobble does not occur and assuming a single base change in the tRNA anticodon, what are all the possible amino acids that might be found in this mutant at the amino acid position in question?
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