Biochemistry: The Molecular Basis of Life
6th Edition
ISBN: 9780190209896
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 19, Problem 55SA
Summary Introduction
To review:
The mechanism through which the proteins that are targeted to the mitochondrial matrix reach their destination.
Introduction:
According to the signal hypothesis, different proteins are destined for secretion to different locations. The movement of the protein can take place across a biological membrane. Initially, they have a stretch of amino acids upstream their actual sequence, and once the proteins reach their destination, this extra sequence, called the signal sequence, is removed. The cleavage of the signal sequence occurs in most proteins, but not in all.
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How do proteins targeted to the mitochondrial matrix reach their destination?
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Chapter 19 Solutions
Biochemistry: The Molecular Basis of Life
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- What thermodynamic force drives the transport of ADP and Pi into the mitochondrial matrix for ATP synthesis?arrow_forwardWhat happens in the mitochondrial intermembrane space?arrow_forwardWhich directions across the mitochondria must H+, ATP, ADP, and Pi travel during active mitochondrial ATP synthesis?arrow_forward
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