Biochemistry: The Molecular Basis of Life
6th Edition
ISBN: 9780190209896
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 19, Problem 47FB
Summary Introduction
To review:
The given blank space in the statement “Posttranslational modifications serve two purposes: to prepare a polypeptide for a specific function and.”
Introduction:
Posttranslational modification is the process in which the polypeptide chain formed through translation undergoes further modifications to form a mature protein. It includes modification of the covalent bonds, removal of a certain portion of peptide, or chemical modifications of the amino acid side chain.
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Chapter 19 Solutions
Biochemistry: The Molecular Basis of Life
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- Why is posttranslational modification necessary for a protein to be functional?arrow_forwardThe figure below shows the titration curve for the amino acid aspartic acid. There are five key points in the titration designated with roman numerals. For each of the statements following the figure, identify the appropriate key point of the titrationarrow_forwardSelenocysteine and pyrolysine differ in the way that they areconverted to their cognate charged tRNAs. Explain.arrow_forward
- What are posttranslational modifications?arrow_forwardA posttranslational modification that directs a polypeptide to a specific location is called a _____________ modification.arrow_forwardSuggest a reason (or reasons) why amino acids polymerize to form proteins that have comparatively few covalent crosslinks in the polypeptide chain.arrow_forward
- The effect of base-pair substitution mutations on protein function varies widely from no detectable effect to the complete loss of a protein function. Why the functional consequences of base-pair substitution vary so widely?arrow_forwardTRUE or FALSE: "The initiation codon for both prokaryotes and eukaryotes is AUG coding for the same amino acid - methionine."arrow_forwardA posttranslational modification that directs a polypeptide toa specific site is called a _____________________modification.arrow_forward
- Compare and contrast cotranslational import of polypeptides with posttranslational import of polypeptides.arrow_forwardThe terminal inverted repeats of a DNA transposon or a retrotransposon bind an enzyme of what superfamily and what function?arrow_forwardThe purine and pyrimidine rings are built from the amino acids aspartate,glutamine, and glycine. Why is serine required for the synthesis of deoxyribonucleotides?arrow_forward
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