Interpretation:
The mechanism for the nucleophilic acyl substitution to form ethyl benzoate and
Concept introduction:
Nucleophilic acyl substitution reactions are the type of substitution reactions that comprise acyl compounds as the reactants along with nucleophile that attacks on electron deficient atoms in the compounds. The synthesis of compound relies upon the type of reactants and reagents that are used during the reactions.
The energy of the product should be low because low energy of a compound increases the stability of a compound. The stability of a compound is the major factor that is responsible for the formation of a compound. The reagents perform numerous functions in reactions like proton abstraction, oxidation, reduction, catalysis, and dehydrogenation.
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EP ORGANIC CHEMISTRY -MOD.MASTERING 18W
- Draw the mechanism of the acid catalyzed hydrolysis of the two following compounds. The products should be a carboxylic acid and an amine or alcohol. of ན་ལེན་arrow_forwardProvide an explanation (in detail) on how base catalysts speed up nucleophilic reactions of carbonyl compounds.arrow_forwardDiazomethane can be used to convert a carboxylic acid to a methyl ester. Propose a mechanism for this reaction.arrow_forward
- The following molecule undergoes an intramolecular reaction in the presence of pyrrolidinium acetate, the protonated form of pyrrolidine. Draw the product of this reaction, assuming that a dehydration reaction takes place.arrow_forwardHow imines and enamines are converted back to carbonyl compounds by hydrolysis with mild acid ?arrow_forwardRank the following esters in order of decreasing reactivity in the first slow step of a nucleophilic acyl substitution reaction (formation of the tetrahedral intermediate):Rank the same esters in order of decreasing reactivity in the second slow step of a nucleophilic acyl substitution reaction (collapse of the tetrahedral intermediate).arrow_forward
- you are performing an acyl nucleophilic substitution reaction using sodium acetate, acetic anhydride, salicyclic acid, and pyridine. show a mechanism for the reaction, and label the nucleophile, acyl compound, and the catalyst.arrow_forwardShow how to synthesize 3-nitro-4-propoxybenzoic acid from phenol, C6H5OH and any reagents that you need.arrow_forwardDraw the reactivity series for nucleophilic substitution at the carbonyl carbon. (You may exclude aldehydes and ketones.)arrow_forward
- In reactions with an aldehyde or ketone to form an imine or an enamine (Section 16.8)arrow_forwardWrite the mechanism for the following reactions: 1. the acid-catalyzed hydrolysis of an imine to a carbonyl compound and a primary amine 2. the acid-catalyzed hydrolysis of an enamine to a carbonyl compound and a secondary amine a. How do the two mechanisms differ?arrow_forwardShow how acid derivatives hydrolyze to carboxylic acids under either acidic or basicconditions. Explain why some acid derivatives (amides, for example) require muchstronger conditions for hydrolysis than other derivatives.arrow_forward
- EBK A SMALL SCALE APPROACH TO ORGANIC LChemistryISBN:9781305446021Author:LampmanPublisher:CENGAGE LEARNING - CONSIGNMENTOrganic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage Learning