Modified Mastering A&P with Pearson eText -- Standalone Access Card -- for Anatomy & Physiology (6th Edition)
6th Edition
ISBN: 9780134388083
Author: Marieb
Publisher: PEARSON
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Textbook Question
Chapter 20.6, Problem 20CYU
Describe the killing mechanism of cytotoxic T cells that involves perforins.
Figure 20.20 Simplified summary of the primary immune response.
Co-stimulation usually requires direct cell-cell interactions; cytokines enhance these and many other events. Although complement, NK cells, and phagocytes are innate defenses, they are enlisted in the fight by cytokines. (For simplicity, only B cell receptors are illustrated.)
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Compare and contrast innate and adaptive immunity. Include three similarities in terms of cell and/or cytokine actions and a discussion of the three hallmark differences (used to define each immune response).
Compare and contrast humoral and cell-mediated immunity. Write three differences and two similarities in terms of function, purpose, types of cells involved, or mechanism. You may write in paragraph form or use a chart/diagram (e'g' Venn diagram) .
Which of the following statements is NOT correct?
Group of answer choices
-Natural killer cells are cytolytic lymphocytes that mediate ADCC
-Neutrophils carry out phagocytosis of C3b-tagged particles
-Macrophages carry out phagocytosis of C3b-tagged particles
-Mast cells produce granules containing the cytotoxin perforin
-B lymphocytes express a receptor for complement proteins
Chapter 20 Solutions
Modified Mastering A&P with Pearson eText -- Standalone Access Card -- for Anatomy & Physiology (6th Edition)
Ch. 20.1 - What distinguishes the innate defense system from...Ch. 20.1 - What is the first line of defense against disease?Ch. 20.2 - What is opsonization and how does it help...Ch. 20.2 - Under what circumstances might NK cells kill our...Ch. 20.2 - What are the cardinal signs of inflammation and...Ch. 20.3 - Name three key characteristics of adaptive...Ch. 20.3 - What is the difference between a complete antigen...Ch. 20.3 - What marks a cell as self as opposed to nonselfCh. 20.4 - What event (or observation) signals that a B or T...Ch. 20.4 - Which of the following T cells would survive...
Ch. 20.4 - Prob. 11CYUCh. 20.4 - In clonal selection, who does the selecting? What...Ch. 20.5 - Why is the secondary response to an antigen so...Ch. 20.5 - Prob. 14CYUCh. 20.5 - Which class of antibody is most abundant in blood?...Ch. 20.5 - List four ways in which antibodies can bring about...Ch. 20.5 - Prob. 17CYUCh. 20.6 - Class II MHC proteins display what kind of...Ch. 20.6 - Which type of T cell is the most important in both...Ch. 20.6 - Describe the killing mechanism of cytotoxic T...Ch. 20.7 - Prob. 21CYUCh. 20.7 - Prob. 22CYUCh. 20 - All of the following are considered innate body...Ch. 20 - The process by which neutrophils squeeze through...Ch. 20 - Antibodies released by plasma cells are involved...Ch. 20 - Which of the following antibodies can fix...Ch. 20 - Which antibody class is abundant in body...Ch. 20 - Small molecules that must combine with large...Ch. 20 - Lymphocytes that develop immunocompetence in the...Ch. 20 - Cells that can directly attack target cells...Ch. 20 - Prob. 9MCCh. 20 - The cell type most often invaded by HIV is a(n)...Ch. 20 - Complement fixation promotes all of the following...Ch. 20 - Using the letters from column B, match the cell...Ch. 20 - Besides acting as mechanical barriers, the skin...Ch. 20 - Explain why attempts at phagocytosis are not...Ch. 20 - What is complement? How does it cause bacterial...Ch. 20 - Interferons are referred to as antiviral proteins....Ch. 20 - Differentiate between humoral and cellular...Ch. 20 - Although the adaptive immune system has two arms,...Ch. 20 - Define immunocompetence and self-tolerance. How is...Ch. 20 - Differentiate between a primary and a secondary...Ch. 20 - Prob. 21SAQCh. 20 - What is the role of the variable regions of an...Ch. 20 - Name the five antibody classes and describe where...Ch. 20 - How do antibodies help defend the body?Ch. 20 - Do vaccines produce active or passive humoral...Ch. 20 - Prob. 26SAQCh. 20 - Describe the specific roles of helper, regulatory,...Ch. 20 - Prob. 28SAQCh. 20 - Prob. 29SAQCh. 20 - What events can result in autoimmune disease?Ch. 20 - Prob. 1CCSCh. 20 - Prob. 2CCSCh. 20 - Prob. 3CCSCh. 20 - Prob. 4CCSCh. 20 - Remember Mr. Ayers, the bus driver from Chapter...
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- Match the immunity concepts: __________ inflammation __________ antibody secretion __________ phagocyte __________ immunological memory __________ vaccination __________ allergy a. neutrophil b. plasma cell c. nonspecific response d. purposely causing memory cell production e. basis of secondary immune response f. nonprotective immune responsearrow_forwardMatch the immunity concept with the best description. ___anaphylactic shock a. recognizes antigen ___immune memory b. inadequate immune response ___autoimmunity c general defense mechanism ___inflammation d. immune response against ones own body ___immune deficiency e. secondary response ___antigen receptor f. acute allergic reaction ___antigen processing g. presenting antigen together with MHC markersarrow_forwardThe Adaptive Immune Response Is a Specific Defense Against Infection Name the class of molecules that includes antibodies, and name the five groups that make up this class.arrow_forward
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- Figure 42.11 Which of the following statements about T cells is false? Helper T cells release cytokines while cytotoxic T cells kill the infected cell. Helper T cells are CD4+, while cytotoxic T cells are CD8+. MHC II is a receptor found on most body cells, while MHC I is a receptor found on immune cells only. The T cell receptor is found on both CD4+ and CD8+ T cells.arrow_forwardWhich of the following is not a part of innate immunity? a. phagocytic cells e. inflammation b. fever f. complement activation c. histamines g. presenting antigen d. cytokines h. all take partarrow_forwardA patient has contracted an upper respiratory infection caused by a virus. Her initial adaptive immune response to the virus is due to what mechanism of immune surveillance?a. The display of viral antigens by naïve B-cells on class I MHC, which is then recognized by helper T-cells that then activate cytotoxic T-cells.b. The display of viral antigens on class I MHC, which is then displayed to sensitized naïve B-cells, leading to the production of antibodies.c. The display of viral antigens on class II MHC by a sensitized naïve B-cell, which is then activated by a helper T-cell primed to the same antigen to begin producing antibodies.d. The display of viral antigens on class I MHC, which is then displayed to helper T-cells, leading to the activation of naïve cytotoxic T-cells.arrow_forward
- Adaptive immunity includes both humoral and cell-mediated immune responses, which interact but also have distinct roles in adaptive immunity. Identify the example of a strictly cell-mediated immune response. A. A cytotoxic T cell destroys an infected host cell. B. A helper T cell activates a B cell. C. A B cell gives rise to plasma cells, which release antibodies. D. An antigen is taken in by an antigen-presenting cell.arrow_forwardIf an individual failed to develop a thymus because of a genetic defect, what would happen to the immune responses mediated by antibodies and those mediated by cytotoxic T cells? Hint: Think how helper T cells and B cells are functionally related,arrow_forwardWith the aid of a hand drawn diagram, briefly explain how T cells are primed or activated by B cells. In your response, briefly outline the major differences between B and T cell activationarrow_forward
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