Concept explainers
(a)
Interpretation:
The complete, detailed mechanism for the given reaction and the major product are to be drawn.
Concept introduction:
In a Claisen condensation reaction, an ester with at least two
If the base, in a Claisen condensation, is nucleophilic, it should be identical to the alkoxide leaving group on the ester. If the solvent can be deprotonated to become strongly nucleophilic, it should be the conjugate acid of the base that is used.
(b)
Interpretation:
The complete, detailed mechanism for the given reaction and the major product are to be drawn.
Concept introduction:
In a Claisen condensation reaction, an ester with at least two
If the base in a Claisen condensation is nucleophilic, it should be identical to the alkoxide leaving group on the ester. If the solvent can be deprotonated to become strongly nucleophilic, it should be the conjugate acid of the base that is used.
In a crossed Claisen condensation reaction, the enolate anion that acts as the nucleophile derives from an ester that is different from the ester it attacks.
(c)
Interpretation:
The complete, detailed mechanism for the given reaction and the major product are to be drawn.
Concept introduction:
In a Claisen condensation reaction, an ester with at least two
If the base in a Claisen condensation is nucleophilic, it should be identical to the alkoxide leaving group on the ester. If the solvent can be deprotonated to become strongly nucleophilic, it should be the conjugate acid of the base that is used.
In a crossed Claisen condensation reaction, the enolate anion that acts as the nucleophile derives from an ester that is different from the ester it attacks.
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