(a)
Interpretation:
How to synthesize the given peptide sequence is to be determined.
Concept introduction:
Proteins are large molecules that are constructed from the amino acids. The amino acids are joined by group characteristics of amides in a stable protein. Since amides are least reactive acid derivative, it requires relatively extreme conditions to hydrolyze them. To synthesize protein, various amino acids are coupled by dehydration, which is catalyzed by DCC. (Remember DCC is a good dehydrating agent, so it is used as a coupling agent in many reactions.) In this reaction, the
(b)
Interpretation:
How to synthesize the given peptide sequence is to be determined.
Concept introduction:
Proteins are large molecules that are constructed from the amino acids. The amino acids are joined by group characteristics of amides in a stable protein. Since amides are least reactive acid derivative, it requires relatively extreme conditions to hydrolyze them. To synthesize protein, various amino acids are coupled by dehydration, which is catalyzed by DCC. (Remember DCC is a good dehydrating agent, so it is used as a coupling agent in many reactions.) In this reaction, the
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