Interpretation:
The preparation of
Concept Introduction:
Gabriel synthesis is used to prepare primary
The reaction starts with the potassium salt of phthalimide. It has a nucleophilic nitrogen atom having a negative charge.
The potassium salt of phthalimide reacts with a primary
Further reaction hydrazine forms the required primary amine.
Aryl halides do not react by this method since nucleophilic substitution does not take place on
Want to see the full answer?
Check out a sample textbook solutionChapter 22 Solutions
Loose Leaf for Organic Chemistry
- Show how the malonic ester synthesis is used to prepare 2-benzylbutanoic acid.Sarrow_forwardGiven this retrosynthetic analysis, show how meclizine can be synthesized from the four named organic starting materials.arrow_forwardPropose a synthesis of the vitamin A precursor from this allylic chloride and ethyl acetoacetatearrow_forward
- What reaction sequence will form dibenylamine from benzoic acid in high yieldarrow_forwardShow how you would use an acid chloride as an intermediate to synthesize(a) N-phenylbenzamide (PhCONHPh) from benzoic acid and anilinearrow_forwardPropose the structure of a starting material that would allow you to use the procedures given to synthesize acetaminophenarrow_forward
- Macroscale and Microscale Organic ExperimentsChemistryISBN:9781305577190Author:Kenneth L. Williamson, Katherine M. MastersPublisher:Brooks ColeOrganic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage Learning
- EBK A SMALL SCALE APPROACH TO ORGANIC LChemistryISBN:9781305446021Author:LampmanPublisher:CENGAGE LEARNING - CONSIGNMENT