Loose Leaf for Organic Chemistry
Loose Leaf for Organic Chemistry
10th Edition
ISBN: 9781259626548
Author: Francis A Carey Dr., Robert M. Giuliano
Publisher: McGraw-Hill Education (edition 10)
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Chapter 22, Problem 32P
Interpretation Introduction

Interpretation:

The structure of the conjugate acid of carnosine is to be drawn.

Concept introduction:

An acidic substance in a reaction donates a proton, whereas base in a reaction accepts a proton. The elimination of a proton leads to the formation of a conjugate base. When the base accepts a proton, the species formed is known as conjugate acid.

The Ka value is large for strong acids and small for weak acids. The stronger acid has a lower value of pKa and the weaker acid has a higher pKa value.

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What is the pKa of the conjugate acid of the reaction?
The pKa values of the carboxylic acid groups of oxaloacetic acid are 2.22 and 3.98. a. Which carboxyl group is the stronger acid? b. The amount of hydrate present in an aqueous solution of oxaloacetic acid depends on the pH of the solution: 95% at pH 0, 81% at pH 1.3, 35% at pH 3.1, 13% at pH 4.7, 6% at pH 6.7, and 6% at pH 12.7. Explain this pH dependence.
The pKa values of the carboxylic acid groups of oxaloacetic acid are 2.22 and 3.98.a. Which carboxyl group is the stronger acid?b. The amount of hydrate present in an aqueous solution of oxaloacetic acid depends on the pH of the solution: 95% at pH 0, 81% at pH 1.3, 35% at pH3.1, 13% at pH 4.7, 6% at pH 6.7, and 6% at pH 12.7. Explain this pH dependence.
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