(a)
Interpretation:
The method of preparation of given compound using malonic ester synthesis has to be stated.
Concept introduction:
Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered
(b)
Interpretation:
The method of preparation of given compound using malonic ester synthesis is to be stated.
Concept introduction:
Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through
(c)
Interpretation:
The method of preparation of given compound using malonic ester synthesis is to be stated.
Concept introduction:
Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through
(d)
Interpretation:
The method of preparation of given compound using malonic ester synthesis is to be stated.
Concept introduction:
Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through
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Organic Chemistry (9th Edition)
- Show how you would use an acid chloride as an intermediate to synthesize) phenyl propionate (CH3CH2COOPh) from propionic acid and phenol.arrow_forwardDraw the two ethyl esters which could be used to make the mixed Claisen product shown below.arrow_forwardWhy is pyridine added to the following reaction?arrow_forward
- Draw the alkyl bromide(s) you would use in a malonic ester synthesis of ethyl 3-methylbutanoate.arrow_forwardShow the product formed as a result of the reaction between propanoic acid and benzylalcohol in an acidic environment by writing down the reaction mechanism.arrow_forwardWhy is the reaction of the type shown below usually done? a.To make an aldehyde or ketone less water soluble b.To make the molecule more reactive c.To protect a ketone or aldehyde carbonyl d.To increase the oxygen content e.To make the alpha hydrogens more acidicarrow_forward
- In the Michael reaction, an alpha-beta unsaturated aldehyde would be considered the _____________ in the reaction. Select one: a. nucleophile b. electrophile c. acid d. base e. None of thesearrow_forwardShow how the malonic ester synthesis can be used to prepare 3-phenylpropanoic acid.arrow_forwardExplain why a Lewis acid is necessary in this aldol reaction. Include a structure formed by the Lewis Acid and one of the reactants that is key to your discussion. R group is p-methoxyphenyl to make p-methoxybenzaldehyde (reactant). R' is phenyl.arrow_forward
- Organic Chemistry: A Guided InquiryChemistryISBN:9780618974122Author:Andrei StraumanisPublisher:Cengage LearningOrganic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage Learning