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Introduction:
The inflow of sodium (Na+) ions in the plasma membrane through the membrane channel regulates the depolarization of nervous and muscular systems and their function. It is the main cation present in the extracellular fluid (ECF) and associated with regulation of blood plasma osmolarity. Increased concentration of sodium raises the osmolarity of the blood. Also, it regulates the level and distribution of total body water among several fluid compartments. Gradients of Na+ ions across the cell generate potential energy that helps to transport other solutes. Also, it regulates body heat and pH of the ECF.
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