Concept explainers
Interpretation:
The structure of compound
Concept introduction:
Ruff degradation is a process in which an aldose is converted into another aldose containing one carbon less than the starting aldose. In this process, an aldose is converted into aldonic acid by oxidation with
Killani Fischer synthesis is the three step process: conversion of aldose into cyanohydrins; hydrolysis; and reduction. The overall use of Killani Fischer synthesis is to synthesize two diastereomeric aldoses with an increased asymmetric carbon from an aldose.
Want to see the full answer?
Check out a sample textbook solutionChapter 24 Solutions
Organic Chemistry
- Draw the product that is expected when the β-pyranose form of compound A is treated with excess ethyl iodide in the presence of silver oxide. The following information can be used to determine the identity of compound A: The molecular formula of compound A is C6H12O6. Compound A is reducing sugar. When compound A is subjected to a Wohl degradation two times sequentially, Derythrose is obtained. Compound A is epimeric with D-glucose at C3. The configuration at C2 is R.EXPLAIN IN DETAIL.arrow_forward(a) Which of the d-aldopentoses will give optically active aldaric acids on oxidation with HNO3 ?(b) Which of the d-aldotetroses will give optically active aldaric acids on oxidation with HNO3 ?(c) Sugar X is known to be a d-aldohexose. On oxidation with HNO3, X gives an optically inactive aldaric acid. WhenX is degraded to an aldopentose, oxidation of the aldopentose gives an optically active aldaric acid. Determine thestructure of X.(d) Even though sugar X gives an optically inactive aldaric acid, the pentose formed by degradation gives an opticallyactive aldaric acid. Does this finding contradict the principle that optically inactive reagents cannot form opticallyactive products?(e) Show what product results if the aldopentose formed from degradation of X is further degraded to an aldotetrose.Does HNO3 oxidize this aldotetrose to an optically active aldaric acid?arrow_forwardA hexose was obtained after (+)-glyceraldehyde underwent three successive Kiliani–Fischer syntheses. Identify the hexose from the following experimental information: oxidation with nitric acid forms an optically active aldaric acid; a Wohl degradation followed by oxidation with nitric acid forms an optically inactive aldaric acid; and a second Wohl degradation forms erythrose.arrow_forward
- Given the following structure of aldose, (a) how many chiral carbons are there? (b) is it a reducing sugar? and (c) is it an L or D sugar?arrow_forwardAn aldopentose "O", is oxidized with HNO3 to a diacid "P" which is optically active. The compound "O", is also degraded to an aldotetrose "Q" which undergoes another oxidation to an optically inactive diacid "R". Assuming that "O" has the configuration D-(4R); what are the structures of "O" to "R"?arrow_forwardWhich aldoses are oxidized to optically inactive aldaric acids: (a) D-erythrose; (b) D-lyxose; (c) D-galactose?arrow_forward
- Organic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage Learning