BIOCHEM-ACHIEVE(FIRST DAY DISCOUNTED)
9th Edition
ISBN: 2818000069358
Author: BERG
Publisher: MAC HIGHER
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Question
Chapter 25, Problem 8P
Interpretation Introduction
Interpretation:
Sources of atoms in the purine ring should be determined.
Concept introduction:
Purine is a heterocyclic ring, which is composed of a pyrimidine ring fused with an imidazole ring. Adenine and guanine found in DNA and RNA are purines. It is oxidized into uric acid by the action of xanthine oxidase. Further, it is also involved in the formation of certain alkaloids, such as caffeine, and theophylline.
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BIOMOLECULES
- Please answer the questions properly.
- Multiple choice
1. In human beings, what is the major control of de novo pyrimidine nucleotide synthesis?
A. substrate availability
B. feedback inhibition of glutamine-PRPP amidotransferase
C. competitive inhibition of carbamoyl phosphate synthetase II
D. availability of N-acetyl glutamate
2. In patients with Lesch Nyhan Syndrome, purine nucleotides are overproduced and over excreted. The hypoxanthine analogue Allopurinol, which effectively treats gout , has no effect on the severe neurological symptoms of Lesch- Nyhan patients because it does not?
A. decrease de novo pyrimidine synthesis
B. increase PRPP levels (Phosphoribosyl pyrophosphate)
C. Decrease urate synthesis
D. decrease de novo purine synthesis
Chapter 25 Solutions
BIOCHEM-ACHIEVE(FIRST DAY DISCOUNTED)
Ch. 25 - Prob. 1PCh. 25 - Prob. 2PCh. 25 - Prob. 3PCh. 25 - Prob. 4PCh. 25 - Prob. 5PCh. 25 - Prob. 6PCh. 25 - Prob. 7PCh. 25 - Prob. 8PCh. 25 - Prob. 9PCh. 25 - Prob. 10P
Ch. 25 - Prob. 11PCh. 25 - Prob. 12PCh. 25 - Prob. 13PCh. 25 - Prob. 14PCh. 25 - Prob. 15PCh. 25 - Prob. 16PCh. 25 - Prob. 17PCh. 25 - Prob. 18PCh. 25 - Prob. 19PCh. 25 - Prob. 20PCh. 25 - Prob. 21PCh. 25 - Prob. 22PCh. 25 - Prob. 23PCh. 25 - Prob. 24PCh. 25 - Prob. 25PCh. 25 - Prob. 26PCh. 25 - Prob. 27PCh. 25 - Prob. 28PCh. 25 - Prob. 29PCh. 25 - Prob. 30PCh. 25 - Prob. 31PCh. 25 - Prob. 32PCh. 25 - Prob. 33PCh. 25 - Prob. 34PCh. 25 - Prob. 35PCh. 25 - Prob. 36PCh. 25 - Prob. 37PCh. 25 - Prob. 38PCh. 25 - Prob. 39PCh. 25 - Prob. 40PCh. 25 - Prob. 41PCh. 25 - Prob. 42PCh. 25 - Prob. 43PCh. 25 - Prob. 44PCh. 25 - Prob. 45PCh. 25 - Prob. 46PCh. 25 - Prob. 47PCh. 25 - Prob. 48PCh. 25 - Prob. 49PCh. 25 - Prob. 50PCh. 25 - Prob. 51P
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