Fundamentals of Biochemistry: Life at the Molecular Level
Fundamentals of Biochemistry: Life at the Molecular Level
5th Edition
ISBN: 9781118918401
Author: Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher: WILEY
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Chapter 26, Problem 20E

(a)

Summary Introduction

To draw: The structure of the modified base formed after N6 methylation of adenosine residues in mRNA.

Introduction: In eukaryotes, transcription occurs in the nucleus and pre-mRNA is synthesized. This pre-mRNA is further modified before translation in the cytoplasm. N6 methylation of adenosine residues is the common post-transcriptional modification in pre-mRNA sequences of the eukaryotes.

(b)

Summary Introduction

To determine: Whether the modification is expected to alter the RNA’s ability to form the stem-loop structures.

Introduction: In eukaryotes, transcription occurs in the nucleus and pre-mRNA is synthesized. This pre-mRNA is further modified before translation in the cytoplasm. N6 methylation of adenosine residues is the common post-transcriptional modification in pre-mRNA sequences of the eukaryotes.

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