Fundamentals of Biochemistry: Life at the Molecular Level
Fundamentals of Biochemistry: Life at the Molecular Level
5th Edition
ISBN: 9781118918401
Author: Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher: WILEY
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Chapter 26, Problem 4E
Summary Introduction

To determine: The reason behind the promoter efficiency tends to decrease with the number of G.C base pairs in the -10 region of a prokaryotic gene.

Introduction: The promoter is a region of DNA where the RNA polymerase enzyme binds to the initiation of transcription. The nucleotide at this position is designated as one. It consists of a consensus sequence that is conserved and specific. The upstream nucleotides to this region are numbered as negative and downstream nucleotides are numbers as positive.

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