Biochemistry
Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Chapter 3, Problem 31P
Interpretation Introduction

Interpretation:

The difficulty in drawing the conclusions for the conformational changes of protein for a single crystal structure needs to be explained.

Concept introduction:

A conformational change of a protein might be induced by several environmental factors like, pH, temperature, phosphorylation, ligands, etc. conformation can be defined as a certain shape and conformational change can be defined as the transition between two conformations.

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Explain why it is difficult to draw conclusions about the conformational changes of a protein based on a single crystal structure.
Explain how each structure (primary, secondary, tertiary, and quaternary) of a protein affects its properties and how denaturation changes the structure.
Explain why a change in the primary structure of a protein may alter the tertiary structures.  Give an example
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