Genetic Analysis: An Integrated Approach (2nd Edition)
2nd Edition
ISBN: 9780321948908
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter 3, Problem 32P
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The following pedigree describes the inheritance of Lesch-Nyhan syndrome, an x-linked recessive disease. Affected individuals are shaded. what is the probability, that the indicated child (IV.1) will be affected by Lesch-Nyhan syndrome?
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The following X-linked recessive traits are found in fruit flies:vermilion eyes are recessive to red eyes, miniature wings are recessiveto long wings, and sable body is recessive to gray body. A cross wasmade between wild-type males with red eyes, long wings, and graybodies and females with vermilion eyes, miniature wings, and sablebodies. The heterozygous female offspring from this cross, whichhad red eyes, long wings, and gray bodies, were then crossed tomales with vermilion eyes, miniature wings, and sable bodies. Thefollowing data were obtained for the F2 generation (including bothmales and females):1320 vermilion eyes, miniature wings, sable body1346 red eyes, long wings, gray body102 vermilion eyes, miniature wings, gray body90 red eyes, long wings, sable body42 vermilion eyes, long wings, gray body48 red eyes, miniature wings, sable body2 vermilion eyes, long wings, sable body1 red eyes, miniature wings, gray bodyA. Calculate the map distances separating the three genes.B. Is…
The following X-linked recessive traits are found in fruit flies:vermilion eyes are recessive to red eyes, miniature wings are recessiveto long wings, and sable body is recessive to gray body. A cross wasmade between wild-type males with red eyes, long wings, and graybodies and females with vermilion eyes, miniature wings, and sablebodies. The heterozygous female offspring from this cross, whichhad red eyes, long wings, and gray bodies, were then crossed tomales with vermilion eyes, miniature wings, and sable bodies. Thefollowing data were obtained for the F2 generation (including bothmales and females):1320 vermilion eyes, miniature wings, sable body1346 red eyes, long wings, gray body102 vermilion eyes, miniature wings, gray body90 red eyes, long wings, sable body42 vermilion eyes, long wings, gray body48 red eyes, miniature wings, sable body2 vermilion eyes, long wings, sable body1 red eyes, miniature wings, gray bodyWhat information do you know based on the question and your…
Chapter 3 Solutions
Genetic Analysis: An Integrated Approach (2nd Edition)
Ch. 3 - Examine the following diagrams of cells from an...Ch. 3 - Our closest primate relative, the chimpanzee, has...Ch. 3 -
3. In a test of his chromosome theory of...Ch. 3 - Cohesion between sister chromatids, as well as...Ch. 3 - 5. The diploid number of the hypothetical animal...Ch. 3 - 6. An organism has alleles R1 and R2 on one pair...Ch. 3 - Explain how the behavior of homologous chromosomes...Ch. 3 - 8. Suppose crossover occurs between the homologous...Ch. 3 -
9. Alleles A and a are on one pair of autosomes,...Ch. 3 - Prob. 10P
Ch. 3 - Describe the role of the following structures or...Ch. 3 - A womans father has ornithine transcarbamylase...Ch. 3 - In humans, hemophilia A (OMIM 306700) is an...Ch. 3 -
14. A wild-type male and a wild-type female...Ch. 3 - 15. A woman with severe discoloration of her tooth...Ch. 3 - 16. In a large metropolitan hospital, cells from...Ch. 3 - In cats, tortoiseshell coat color appears in...Ch. 3 - 18. The gene causing Coffin–Lowry syndrome (OMIM...Ch. 3 - 19. Four eye-color mutants in Drosophila—apricot,...Ch. 3 - 20. For each pedigree shown,
a. Identify which...Ch. 3 - 21. Use the blank pedigrees provided to depict...Ch. 3 - 22. Figure 3.22 (page 89) illustrates reciprocal...Ch. 3 - 23. In fruit flies, yellow body (y) is recessive...Ch. 3 - 24. In a species of fish, a black spot on the...Ch. 3 - LeschNyhan syndrome (OMIM 300322) is a rare...Ch. 3 - 26. In humans, SRY is located near a...Ch. 3 - 27. In an 1889 book titled Natural Inheritance...Ch. 3 - 30. Drosophila has a diploid chromosome number of...Ch. 3 - 29. A wild-type Drosophila male and female are...Ch. 3 - 28. In Drosophila, the X-linked echinus eye...Ch. 3 - 31. While examining a young tortoiseshell cat, you...Ch. 3 - 32. Redgreen color blindness in humans is...
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- Given the karyotype shown at right, is this a male or a female? Normal or abnormal? What would the phenotype of this individual be?arrow_forwardHuman sex chromosomes are XX for females and XY for males. a. With respect to an X-linked gene, how many different types of gametes can a male produce? b. If a female is homozygous for an X-linked allele, how many different types of gametes can she produce with respect to this allele? c. If a female is heterozygous for an X-linked allele, how many different types of gametes can she produce with respect to this allele?arrow_forwardThe following X-linked recessive traits are found in fruit flies:vermilion eyes are recessive to red eyes, miniature wings are recessiveto long wings, and sable body is recessive to gray body. A cross wasmade between wild-type males with red eyes, long wings, and graybodies and females with vermilion eyes, miniature wings, and sablebodies. The heterozygous female offspring from this cross, whichhad red eyes, long wings, and gray bodies, were then crossed tomales with vermilion eyes, miniature wings, and sable bodies. Thefollowing data were obtained for the F2 generation (including bothmales and females):1320 vermilion eyes, miniature wings, sable body1346 red eyes, long wings, gray body102 vermilion eyes, miniature wings, gray body90 red eyes, long wings, sable body42 vermilion eyes, long wings, gray body48 red eyes, miniature wings, sable body2 vermilion eyes, long wings, sable body1 red eyes, miniature wings, gray bodyWhat topic in genetics does this question address?arrow_forward
- The following X-linked recessive traits are found in fruit flies:vermilion eyes are recessive to red eyes, miniature wings are recessiveto long wings, and sable body is recessive to gray body. A cross wasmade between wild-type males with red eyes, long wings, and graybodies and females with vermilion eyes, miniature wings, and sablebodies. The heterozygous female offspring from this cross, whichhad red eyes, long wings, and gray bodies, were then crossed tomales with vermilion eyes, miniature wings, and sable bodies. Thefollowing data were obtained for the F2 generation (including bothmales and females):1320 vermilion eyes, miniature wings, sable body1346 red eyes, long wings, gray body102 vermilion eyes, miniature wings, gray body90 red eyes, long wings, sable body42 vermilion eyes, long wings, gray body48 red eyes, miniature wings, sable body2 vermilion eyes, long wings, sable body1 red eyes, miniature wings, gray bodyAnalyze data. Make a drawing. Make a calculation.arrow_forwardWhen a white guinea pig is crossed to a yellow guinea pig, all the progeny are cream-colored. From a cross of two such F1’s, the F2 showed 32 white, 66 cream, and 30 yellow guinea pigs. How is this trait inherited? _______________ Identify the genotype of the white guinea pig. ________ Identify the genotype of the yellow guinea pig. ________ Identify the genotype of the cream-colored guinea pig. ________ Identify the genotypes and the corresponding phenotypes of the F2 progeny. Give the genotypic ratio. __________________ Give the phenotypic ratio. ___________________arrow_forwardA man with blood type O (genotype ii) has a father with blood type A and a mother with blood type B. Is this man a legitimate child of these parents? What is a possible phenotype of an individual that results from a woman with type AB blood and a man with type B blood? Explain with diagrams.arrow_forward
- I will be adding two questions here because I asked two of the same questions twice by accident earlier. A man and a woman do not have hemophilioa, but the womans father did. (Hemophilia is X-linked recessive). a) What is the probability that they will have a child with hemophilia? b) Is it possible for any of their daughters to be affected? Explain. A cross between a horse homozygous for red hair and a horse homozygous for white hair results in offspring with the coat colour called roan. When you look at the fur of the roan offspring you see both red and white hairs. What type of inheritance best explains this? a) blending inheritance b)codominance c)incomplete codominance d)multiple allelesarrow_forwardFigure 5.1 presented abbreviated pedigrees looking at the inheritance of X-linked human conditions. El Figure 5.1a initiated with a male who was color blind and had hemophilia A. The grandsons and great-grandsons of this male were either color blind and had hemophilia A, or they had neither condition. a. Which if any individuals in the G Fig. 5.1a pedigree is a double heterozygote? b. Are any of the grandsons or great-grandsons shown in the pedigree the product of recombinant type gametes? c. Do the genes responsible for color blindness and hemophilia A segregate independently? d. If you examined many pedigrees, each starting with a man who was simultaneously color blind and had hemophilia A, do you think any grandsons or great-grandsons would ever have one condition but not the other? L Figure 5.1b initiated with a male who was color blind and had hemophilia B. The grandsons of this male were either only color blind, only had hemophilia B, had both conditions, or they had neither…arrow_forwardIn crosses between mutant mice, you find the following patterns in the genotype for the A locus containing alleles A1, A2, A3 and A4: What would be the best explanation for the inheritance and why?arrow_forward
- Consider a couple: a woman who is homozygous for a recessive mutation that causes X-linked colorblindness, and a man with full color vision (he does not carry a copy of the mutation). a) What is the probability that a son of this couple will be colorblind? b) What is the probability that a daughter of the couple will be colorblind?arrow_forwardIn beetles, an X-linked gene determines body size, with normal size (M)completely dominant to miniature body size (m). Body color is determined by an autosomal gene with two alleles, where B is incompletely dominant to b such that BB beetles are black, Bb beetles are brown and bb beetles are yellow. Male beetles are heterogametic (XY). The following cross is performed: brown, miniature sized body female X brown, normal sized body male Based on this information, which of the following statements is FALSE? Select 3 correct answer(s) Question 3 options: A) 1/8 of the female progeny will have yellow miniature bodies. B) All of the male progeny will have miniature bodies. C) 1/4 of the total progeny will be black. D) 1/4 of the male progeny will have yellow miniature bodies. E) All of the female progeny will have miniature bodies.…arrow_forwardIn the pedigree attached, the shaded symbols represent people affected with a neurological disorder caused by an X-linked recessive allele. The normal allele is D and the recessive allele is d. What are the genotypes of every person in this pedigree? Please explain in as much detail as possible.arrow_forward
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