Genetic Analysis: An Integrated Approach (2nd Edition)
2nd Edition
ISBN: 9780321948908
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Textbook Question
Chapter 3, Problem 20P
For each pedigree shown,
a. Identify which simple pattern of hereditary trans-mission (autosomal dominant, autosomal recessive, X-linked dominant, or X-linked recessive) is most likely to have occurred. Give genotypes for individuals involved in transmitting the trait.
b. Determine which other pattern(s) of transmission is/are possible. For each possible mode of transmission, specify the genotypes necessary for transmission to occur.
c. Identify which pattern(s) of transmission is/are impossible. Specify why transmission is impossible.
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a) What is the mode of inheritance in the following pedigree for the disease trait (autosomal dominant or recessive?)
b) What are the possible genotypes for each individual in the pedigree? (Hint: You can use “A” for dominant allele and “a” for recessive allele)
Y-linked Amelogenesis imperfecta (A), a congenital disorder that affects the formation of the teeth enamel making affected individuals at higher risk for dental cavities and related problems.
X-linked dominant hypophosphatemia (H), a form of rickets or vitamin D deficiency that affects the bones which causes pain, osteoarthritis, and abnormal shapeabnormal shape.
X-linked recessive progressive Duchenne muscular dystrophy (m), a muscular disorder, leading to an irreversible gradual wasting of skeletal muscles.
Hannah, the same as her mom, is heterozygous for both X-linked traits. While her dad is suffering from both muscular dystrophy and hypophosphatemia.
Hannah's husband, Joey has a mom suffering from musculardystrophy regardless of having normal bone conditions. His dad has been blessed with strong muscles and bones, however, he is suffering from amelogenesis imperfecta.
What are the complete genotypes of each person?a. Joey's momb. Joey's dadc. Joeyd. Hannah's mome. Hannah's dad f.…
What is the pattern of inheritance? Please Provide a specific reason that justifies your selection of this pattern of inheritance as the correct one, and also explain why each of the other two alternatives are not correct. As part of your answer, you must include the phenotypic ratio, including the sex of the offspring, that you would expect to find in each of the three possible scenarios.
Please specify whether this pattren of inheritance is (i) rare X-linked recessive, (ii) sex-influenced, or (iii) sex-limited.
Chapter 3 Solutions
Genetic Analysis: An Integrated Approach (2nd Edition)
Ch. 3 - Examine the following diagrams of cells from an...Ch. 3 - Our closest primate relative, the chimpanzee, has...Ch. 3 -
3. In a test of his chromosome theory of...Ch. 3 - Cohesion between sister chromatids, as well as...Ch. 3 - 5. The diploid number of the hypothetical animal...Ch. 3 - 6. An organism has alleles R1 and R2 on one pair...Ch. 3 - Explain how the behavior of homologous chromosomes...Ch. 3 - 8. Suppose crossover occurs between the homologous...Ch. 3 -
9. Alleles A and a are on one pair of autosomes,...Ch. 3 - Prob. 10P
Ch. 3 - Describe the role of the following structures or...Ch. 3 - A womans father has ornithine transcarbamylase...Ch. 3 - In humans, hemophilia A (OMIM 306700) is an...Ch. 3 -
14. A wild-type male and a wild-type female...Ch. 3 - 15. A woman with severe discoloration of her tooth...Ch. 3 - 16. In a large metropolitan hospital, cells from...Ch. 3 - In cats, tortoiseshell coat color appears in...Ch. 3 - 18. The gene causing Coffin–Lowry syndrome (OMIM...Ch. 3 - 19. Four eye-color mutants in Drosophila—apricot,...Ch. 3 - 20. For each pedigree shown,
a. Identify which...Ch. 3 - 21. Use the blank pedigrees provided to depict...Ch. 3 - 22. Figure 3.22 (page 89) illustrates reciprocal...Ch. 3 - 23. In fruit flies, yellow body (y) is recessive...Ch. 3 - 24. In a species of fish, a black spot on the...Ch. 3 - LeschNyhan syndrome (OMIM 300322) is a rare...Ch. 3 - 26. In humans, SRY is located near a...Ch. 3 - 27. In an 1889 book titled Natural Inheritance...Ch. 3 - 30. Drosophila has a diploid chromosome number of...Ch. 3 - 29. A wild-type Drosophila male and female are...Ch. 3 - 28. In Drosophila, the X-linked echinus eye...Ch. 3 - 31. While examining a young tortoiseshell cat, you...Ch. 3 - 32. Redgreen color blindness in humans is...
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