BIOCHEM-ACHIEVE(FIRST DAY DISCOUNTED)
BIOCHEM-ACHIEVE(FIRST DAY DISCOUNTED)
9th Edition
ISBN: 2818000069358
Author: BERG
Publisher: MAC HIGHER
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Chapter 4, Problem 43P
Interpretation Introduction

Interpretation:

The sequence of the corresponding radiolabeled peptide needs to be determined.

Concept introduction:

A sequence of three DNA or RNA nucleotides is called a Codon. The three-nucleotide sequence or codon corresponds to a specific amino acid, and these codons are interpreted by the tRNA. The tRNA also contains the anticodon which recognizes and interprets the codons on the mRNA. The tRNA binds its corresponding codon on the ribosome and they decode the mRNA until the whole sequence is coded.

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An extra piece. In one type of mutation leading to a form of thalassemia, the mutation of a single base (G to A) generates a new 3' 3' splice site (blue in the illustration below) akin to the normal one (yellow) but farther upstream. Normal 3' end of intron 5' CCTATTGGTCTATTITCCACCCITAGGCTGCTG 3' 5' CCTATTAGTCTAIIIICCACCCTTAGGCTGCTG 3' What is the amino acid sequence of the extra segment of protein synthesized in a thalassemic patient having a mutation leading to aberrant splicing? The reading frame after the splice site begins with TCT.
tRNA enzyme. Any given aminoacyl-tRNA synthetase: a. Attaches the amino acid to the 5′-end '5end of the tRNA b. Always recognizes only one specific tRNA c. Recognizes all tRNA molecules d. Forms an ester linkage between the amino acid and the tRNA
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