Microbiology: An Evolving Science (Fourth Edition)
Microbiology: An Evolving Science (Fourth Edition)
4th Edition
ISBN: 9780393615098
Author: John W. Foster, Joan L. Slonczewski
Publisher: W. W. Norton & Company
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Chapter 7, Problem 6RQ
Summary Introduction

To review:

The mechanism of topoisomerases and the drug that targets them.

Introduction:

Topoisomerase is an enzyme responsible for the unwinding of supercoiled DNA (deoxyribonucleic acid). Supercoiling is helpful in packing the long strands of DNA in a compact form. Topoisomerases play a major role in the replication of DNA. There are two types of topoisomerases, namely type 1 and type 2 topoisomerase.

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