Biochemistry: Concepts and Connections (2nd Edition)
Biochemistry: Concepts and Connections (2nd Edition)
2nd Edition
ISBN: 9780134641621
Author: Dean R. Appling, Spencer J. Anthony-Cahill, Christopher K. Mathews
Publisher: PEARSON
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Chapter 8, Problem 10P
Interpretation Introduction

Interpretation:

The explanation for the observation that kcat increases rapidly between pH 6 and 7 and remains constant at higher pH. Km also increases rapidly between pH 8 and 10 should be determined.

Concept introduction:

The pH is the main factor to decide the activity of an enzyme moreover at optimum pH the activity of the enzyme is maximum which indicates that it is converting more and more substrate to product.

The activity of the enzyme can be determined through Kcat/KM, higher the value of Kcat give the maximum activity of the enzyme and this activity lowers down with a decrease in value of Kcat.

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