Biochemistry: The Molecular Basis of Life
Biochemistry: The Molecular Basis of Life
6th Edition
ISBN: 9780190209896
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 8, Problem 71TQ
Summary Introduction

To Review:

The production of NADH(reduced nicotinamide adenine dinucleotide) and NADPH(reduced nicotinamide adenine dinucleotide phosphate)duringglycolysis and pentose phosphate pathway, respectively.

Introduction:

Glycolysis and pentose phosphate pathway both are the biochemical reactions where glucose breaks down. In glycolysis, glucose isbroken downto pyruvate and NADH along with twomolecules of ATP (adenosine triphosphate). On the hand, in pentose phosphate pathwa, yADPHis produced along with ribose-5-phosphate, which is essential for nucleotide and nucleic acid synthesis.

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Question 1: The overall process enabled by the glyoxylate cycle is: (2acetyl-CoA) + (NAD+) + (2H2O) → (succinate) + (2CoA) + (NADH) + (2H+) Dissect this process further by writing down all of the reactions that are actually involved in making one succinate from two acetyl-CoA units. Show chemical structure for all intermediates.

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Biochemistry: The Molecular Basis of Life

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