Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Textbook Question
Chapter ST.2, Problem 3DQ
If you were acting as a defense lawyer in a murder case that used DNA profiling as evidence against the defendant, how would you explain to the jury the factors that might alter their interpretation of the crime scene DNA profile?
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Chapter ST Solutions
Concepts of Genetics (12th Edition)
Ch. ST.1 - What is the difference between innate immunity and...Ch. ST.1 - What evidence demonstrates that CRISPR-Cas is an...Ch. ST.1 - Prob. 3RQCh. ST.1 - Why was the type II CRISPR-Cas9 system of S....Ch. ST.1 - Prob. 5RQCh. ST.1 - What is a single guide RNA, and what role does it...Ch. ST.1 - What is the difference between nonhomologous...Ch. ST.1 - Prob. 8RQCh. ST.1 - Prob. 9RQCh. ST.1 - Prob. 1DQ
Ch. ST.1 - Prob. 2DQCh. ST.1 - What ethical and safety considerations must be...Ch. ST.1 - Recall (from Chapter 18) how miRNAs and the...Ch. ST.1 - Describe two different ways in which engineered...Ch. ST.1 - Consider the following human genetic diseases:...Ch. ST.1 - What are the different concerns about off-target...Ch. ST.2 - What is VNTR profiling, and what are the...Ch. ST.2 - Prob. 2RQCh. ST.2 - Describe capillary electrophoresis. How does this...Ch. ST.2 - What are the advantages and limitations of...Ch. ST.2 - Prob. 5RQCh. ST.2 - Explain why mitochondrial DNA profiling is often...Ch. ST.2 - Prob. 7RQCh. ST.2 - Describe the database system known as CODIS. What...Ch. ST.2 - Prob. 9RQCh. ST.2 - Prob. 10RQCh. ST.2 - Given the possibility that synthetic DNA could be...Ch. ST.2 - Prob. 2DQCh. ST.2 - If you were acting as a defense lawyer in a murder...Ch. ST.2 - The phenomena of somatic mosaicism and chimerism...Ch. ST.3 - What is pharmacogenomics, and how does it differ...Ch. ST.3 - Describe how the drug Herceptin works. What types...Ch. ST.3 - Prob. 3RQCh. ST.3 - Prob. 4RQCh. ST.3 - Prob. 5RQCh. ST.3 - Prob. 6RQCh. ST.3 - Why is it necessary to examine gene-expression...Ch. ST.3 - Prob. 8RQCh. ST.3 - Prob. 1DQCh. ST.3 - Prob. 2DQCh. ST.3 - How can we ensure that a patients privacy is...Ch. ST.3 - As gene tests and genomic sequences become more...Ch. ST.4 - How do genetically modified organisms compare with...Ch. ST.4 - Prob. 2RQCh. ST.4 - Prob. 3RQCh. ST.4 - Prob. 4RQCh. ST.4 - Describe the mechanisms by which the Cry proteins...Ch. ST.4 - Prob. 6RQCh. ST.4 - Prob. 7RQCh. ST.4 - Describe how plants can be transformed using...Ch. ST.4 - How do positive and negative selection techniques...Ch. ST.4 - Prob. 10RQCh. ST.4 - What are the laws regulating the development,...Ch. ST.4 - Do you think that foods containing GM ingredients...Ch. ST.4 - Prob. 3DQCh. ST.5 - What is gene therapy?Ch. ST.5 - Prob. 2RQCh. ST.5 - When treating a person by gene therapy, is it...Ch. ST.5 - Describe two ways that therapeutic genes can be...Ch. ST.5 - Explain how viral vectors can be used for gene...Ch. ST.5 - Prob. 6RQCh. ST.5 - Explain an example of a successful gene therapy...Ch. ST.5 - Prob. 8RQCh. ST.5 - Prob. 9RQCh. ST.5 - Prob. 10RQCh. ST.5 - Prob. 11RQCh. ST.5 - Prob. 1DQCh. ST.5 - Who should be treated by gene therapy? What...Ch. ST.5 - The lifetime costs for treatment of conditions...Ch. ST.5 - Should CRISPR-Cas or other techniques be used for...Ch. ST.5 - Prob. 5DQCh. ST.6 - What are RFLP markers and how were they used to...Ch. ST.6 - Why was information from Nancy Wexlers large...Ch. ST.6 - How do aggregates of mHTT protein form?Ch. ST.6 - Why are the results from the inducible mouse model...Ch. ST.6 - Based on the results from mouse models, is it...Ch. ST.6 - What do the results from creating transgenic mice...Ch. ST.6 - What steps lead from the binding of the mHTT...Ch. ST.6 - Summarize the approaches to therapy designed to...Ch. ST.6 - There are nine known progressive neurodegenerative...Ch. ST.6 - Prob. 2DQCh. ST.6 - Prob. 3DQCh. ST.6 - Why is there an inverse correlation between the...Ch. ST.6 - Discuss the ethical issues raised by the use a...
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- Since DNA anaylsis is specific to human body fluids such as blood, why do Crime Scene Investigators even bother with doing field test for biological fluids? Why not submit all samples that might have any kind biological fluid to the lab?arrow_forwardWhat are three major limitations of forensic DNA profiling?arrow_forwardState the five basic steps of DNA fingerprinting using the RFLP method. Why do you think the PCR method is of more use in crime scene investigations?arrow_forward
- Write an analysis of the results, interpreting what you see in the smaller gell focusing on 6A, 6B, 6C, 6D and 6CS ( Crime Scene) DNA fragments in the agrose gell. Who is the guilty suspect and why ?arrow_forwardDiscuss the principle of DNA fingerprinting. How would you use the technique to find out a criminal in forensic studies ? Explain.arrow_forwardDNA profiling identifies a person by the similar parts of his or her DNA True Falsarrow_forward
- The Evidence shows which suspect was at the crime scene? ( image of murder investigation) A) suspect A B) suspect B C) suspect C D) none were at the crime scene Which of the following choices most likely lists the sizes of the four DNA fragments in lane 6 ( second image) of this agarose gel stained with ethidium bromide? ( Note: the well that the DNA was loaded into is at the top of the gel image). A) 100 bp, 300 bp, 450 bp, 600 bp. B) 300 bp, 400 bp, 100 bp, 600 bp C) 600 bp, 450 bp, 300 bp, 100 bp D) 400 bp, 300 bp, 600 bp, 100 bp E) DNA fragment size can't be estimated using an agarose gel.arrow_forwardWhen forensic experts work with a blood sample, what part of it do they use for PCR; red blood cells, white blood cells, or proteinaceous antibodies? If trying to find a tandem repeat segment, why would you pick one choice other another?arrow_forwardRefer to the DNA profiles comparing the DNA obtained from the three suspects with the crime-scene DNA. Use a ruler to align the bands found under the crime-scene DNA with any of the bands found in the suspects’ DNA. Place the ruler at the bottom of the bands. Take notes on whether any of the suspects’ DNA shares the same bands as the crime-scene DNA. Analyze your notes on each suspect’s DNA profile. Do any suspects share all the DNA bands found in the evidence DNA?arrow_forward
- How are genetic forensics inaccurate?arrow_forwardWhich of the following criteria do you feel is the most important one to optimize for a DNA profiling methods? Speed Discriminating power Sensitivity Cost False Positive Ratearrow_forwardThe two main functions of biometrics are ___________and _________ .arrow_forward
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