Concept explainers
(a)
Interpretation:
How to carry out the given transformation which may require more than one reaction is to be shown.
Concept introduction:
Usually secondary and tertiary alcohols show dehydration reaction through E1 mechanism. In presence of any strong acid, the dehydration of alcohols occurs. In step one, the strong acid protonates the hydroxyl oxygen atom and converts it to a good leaving group. In the next step, the leaving group leaves resulting in the formation of a carbocation intermediate. The carbocation intermediate which is formed can rearrange itself via 1, 2-hydride shift or 1, 2-methyl shift to yield a more stable carbocation. Third step is a deprotonation step in which water removes the proton which is adjacent to the carbocation and forms the most substituted
(b)
Interpretation:
How to carry out the given transformation requiring more than one reaction is to be shown.
Concept introduction:
Alcohols can be converted to least substituted alkene via Hoffman elimination. Hoffman elimination requires an amine precursor which can be generated from the starting alcohol after using
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ORGANIC CHEMISTRY E-BOOK W/SMARTWORK5
- By following the curved red arrows, draw the product(s) of each of the following reaction steps. Also indicate which species is the electrophile and which is the nucleophile.arrow_forwardTextbook problem: Suggest short series of reactions that would be expected to transform the material on the right into the desired product shown on left.arrow_forwardplease draw the complete, detailed mechanism and the product of this reaction.arrow_forward
- Propose a mechanism for the reaction shown here, which takes place under conditions that favor anarrow_forward(SYN) In the reaction shown here, the aromatic ring has just one chemically distinct, aromatic H, so a single electrophilic aromatic substitution will lead to just a single product. With this in mind, supply the missing reagentsneeded to carry out the transformation.arrow_forwardBy following the curved red arrows, draw the product(s) of each of the following reaction steps:arrow_forward
- draw mechanism for below reaction, name the final productarrow_forwardHelp, explain in detail please. Thank you! Did the overal reaction shown here occur by and SN2, Sn1, E2, or E1 mechanism? How do you know? Draw the complete, detailed mechanism to account for the formation of both products.arrow_forward(SYN) Show how to carry out this transformation using any reagents necessaryarrow_forward
- The first step should be proton transfer. As I included in my work and the second step I think should be nucleophilic attack but I don't know how to continue on from there. Please but problem as a list of reactionsarrow_forwarddraw a full reaction mechanism with arrow pushing for each step of the synthesis. Please answer very soon will give rating surelyarrow_forwardPlease help would and explain problemarrow_forward
- Organic Chemistry: A Guided InquiryChemistryISBN:9780618974122Author:Andrei StraumanisPublisher:Cengage Learning