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Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052

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BuyFindarrow_forward

Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052
Chapter 10.4, Problem 2GR
Textbook Problem
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In addition to phenylalanine, high levels of what other compound(s) might show up in the urine of those with PKU? Why?

Summary Introduction

To explain: the other compounds that might come up in the urine of PKU patients and the reason for their appearance.

Introduction: Phenylketonuria (PKU) is a genetic disorder that is inherited from one generation into the next. PKU is caused because of the mutation in the gene that codes for the synthesis of an enzyme required for metabolism of phenylalanine. This causes synthesis of the defective enzyme and proper metabolism of phenylalanine is not achieved.

Explanation of Solution

Pictorial representation: Fig. 1 represents the chemical reactions depicting fate of phenylalanine in patients suffering from phenylketonuria.

Fig. 1: Fate phenylalanine in patients suffering from phenylketonuria...

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