CAMPBELL MASTERING BIOLOGY ACCESS>I<
CAMPBELL MASTERING BIOLOGY ACCESS>I<
18th Edition
ISBN: 9781323766286
Author: Pearson
Publisher: PEARSON
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Chapter 14, Problem 13TYU

SYNTHESIZE YOUR KNOWLEDGE

Chapter 14, Problem 13TYU, SYNTHESIZE YOUR KNOWLEDGE Some mutations result in proteins that function well at one temperature

Some mutations result in proteins that function well at one temperature but are nonfunctional at a different (usually higher) temperature. Siamese cats have such a “temperature-sensitive” mutation in a gene encoding an enzyme that makes dark pigment in the fur. The mutation results in the breed's distinctive point markings and lighter body color (see the photo). Using this information and what you learned in the chapter, explain the pattern of the cat’s fur pigmentation.

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ou now have an understanding of Genomes, DNA Replication, Transcription, Translation, and Regulation of Genes. How would you reprogram skin cells to create cells which look and behave like brain cells (neurons)?  What would you change/modify to reprogram a skin cell to a neuron? How would you introduce the change/modification into the skin cells to transform them into neurons?
think about this: if you know the amino acid sequence of a protein can you predict with 100% certainty the DNA sequence of the gene that codes for it? Would knowing the amino acid sequence help you identify the gene?
Suppose you are studying two different mutations in a gene that codes for a protein. In the first, a nonsense mutation occurs near the beginning of the gene. In the second, a nonsense mutation occurs near the end of a gene. Which mutation is more likely to affect the proteins function? Why?

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Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY