CAMPBELL MASTERING BIOLOGY ACCESS>I<
CAMPBELL MASTERING BIOLOGY ACCESS>I<
18th Edition
ISBN: 9781323766286
Author: Pearson
Publisher: PEARSON
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Chapter 14, Problem 6TYU
Summary Introduction

Introduction:

The unit of genetic code, which has three nucleotides that code for amino acids, is called codon. The mRNA (messenger ribonucleic acid) got attached to the ribosomal complex in the cytoplasm. The transfer RNA conveys amino acids to the ribosomal complex where the pairing of an anticodon of tRNA (transfer ribonucleic acid) takes place with complementary codon of the messenger RNA.

Again, new amino acid is carried by tRNA, which again binds to the complementary codon of mRNA. In this way, amino acids get linked to each other, forming the long chain of the polypeptides.

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Given the following DNA sequence: ATCGGATCCGGTTAACTATTTAAAGCA a. predict the compliment strand of dna (coding strand) b. predict the transcribed product of the coding strand (mRNA transcript) c. given the genetic code table, predict the amino acid sequence of the transcript d. predict the amino acid sequence if the A underlined became deleted
Given the template DNA sequence:  3’ - TAC - CAG - GTT - ACC - ATC - 5’    A.) What will be the mRNA requence corresponding to the template DNA sequence? B.) What is the amino acid sequence in letter A? ( e.g. Arg, Phe, etc.)  C.) If the coding sequence of the dsDNA will "serve" as the template for transcription, what is the corresponding mRNA sequence? D.) With the mRNA transcript in letter C, what will be the amino acid sequence?  ( e.g. Arg, Phe, etc.)
Given is the 30 nucleotides in the human gene for hemoglobin (the oxygen-carrying protein in the red blood cells): 5’ TAC-CAC-GTG-GAC-TGA-GGA-CTC-CTC-TTC-AGA 3’ a. What is the complementary strand? b.Deduce the mRNA in this coding region. c.What is the amino acid sequence based on this mRNA? d. A very important mutation in human hemoglobin occurs in this DNA sequence, where the T at nucleotide 20 is replace with an A.  The mutant hemoglobin is called sickle cell hemoglobin and is associated with severe anemia. What is the amino acid replacement that results in sickle-cell hemoglobin?

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