Genetics: From Genes to Genomes, 5th edition
Genetics: From Genes to Genomes, 5th edition
5th Edition
ISBN: 9780073525310
Author: Leland H. Hartwell, Michael L. Goldberg, Janice A. Fischer, Leroy Hood, Charles F. Aquadro
Publisher: McGraw-Hill Education
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Chapter 18, Problem 21P
a. Explain the difference between maternal inheritance of organelle DNAs and maternal effect inheritance.
b. How do the inheritance patterns of phenotypes caused by mitochondrial genes differ from those caused by
maternal effect genes?
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Describe the inheritance pattern of maternal effect genes. Explainhow the maternal effect occurs at the molecular and cellular level.What are the expected functional roles of the proteins that areencoded by maternal effect genes?
(a) How does the duplication of individual genes occur? (b) individual that inherit a genetic condition known as xeroderma pigmentosum exhibit an extreme sensitivity to sunlight exposure and often develop skin cancer by the age of 10. What repair pathway is most likely disrupted as a result of such mutation? Explain why?
a. What DNA sequences are commonly found at human centromeric regions?b. What functions do the two centromere-associatedcomplexes, cohesin and the kinetochore, play inchromosome mechanics?
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Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY