(a) Interpretation: A mechanism for the reaction of two equivalents of the methyllithium with carboxylic acids to produce ketones is to be stated. Concept introduction: Organolithium reagents are very reactive organometallic compounds. These compounds attack directly on the carbonyl carbon of carbonyl compounds. The organolithium compounds are very strong base and therefore, undergo acid-base reactions very quickly.

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Answer 1

Question

Chapter 20, Problem 20.51AP

Interpretation Introduction

(a)

Interpretation:

A mechanism for the reaction of two equivalents of the methyllithium with carboxylic acids to produce ketones is to be stated.

Concept introduction:

Organolithium reagents are very reactive organometallic compounds. These compounds attack directly on the carbonyl carbon of carbonyl compounds. The organolithium compounds are very strong base and therefore, undergo acid-base reactions very quickly.

Interpretation Introduction

(b)

Interpretation:

The product of the given reaction is to be stated.

Concept introduction:

Organolithium reagents are very reactive organometallic compounds. These compounds attack directly on the carbonyl carbon of carbonyl compounds. The organolithium compounds are very strong base and therefore, undergo acid-base reactions very quickly.

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Students have asked these similar questions

(a) Account for the following :(i) Propanal is more reactive than propanone towards nucleophilic reagents.(ii) Electrophilic substitution in benzoic acid takes place at meta position.(iii) Carboxylic acids do not give characteristic reactions of carbonyl group.(b) Give simple chemical test to distinguish between the following pairs of compounds:(i) Acetophenone and benzaldehyde(ii) Benzoic acid and ethylbenzoate.

(a) Why are alkyl halides insoluble in water? (b) Why is Butan-l-ol optically inactive but Butan-2-ol is optically active? (c) Although chlorine is an electron withdrawing group, yet it is ortho-, Para- directing in electrophilic aromatic substitution reaction. Why?

(a) Write the chemical reaction involved in Wolff-Kishner reduction.(b) Arrange the following in the increasing order of their reactivity towards nucleophilic addition reaction:C6H5COCH3, CH3— CHO, CH3COCH3(c) Why carboxylic acid does not give reactions of carbonyl group?

Answer 2

Question

Chapter 20, Problem 20.51AP

Interpretation Introduction

(a)

Interpretation:

A mechanism for the reaction of two equivalents of the methyllithium with carboxylic acids to produce ketones is to be stated.

Concept introduction:

Organolithium reagents are very reactive organometallic compounds. These compounds attack directly on the carbonyl carbon of carbonyl compounds. The organolithium compounds are very strong base and therefore, undergo acid-base reactions very quickly.

Interpretation Introduction

(b)

Interpretation:

The product of the given reaction is to be stated.

Concept introduction:

Organolithium reagents are very reactive organometallic compounds. These compounds attack directly on the carbonyl carbon of carbonyl compounds. The organolithium compounds are very strong base and therefore, undergo acid-base reactions very quickly.

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Answer 3

Question

Chapter 20, Problem 20.51AP

Interpretation Introduction

(a)

Interpretation:

A mechanism for the reaction of two equivalents of the methyllithium with carboxylic acids to produce ketones is to be stated.

Concept introduction:

Organolithium reagents are very reactive organometallic compounds. These compounds attack directly on the carbonyl carbon of carbonyl compounds. The organolithium compounds are very strong base and therefore, undergo acid-base reactions very quickly.

Interpretation Introduction

(b)

Interpretation:

The product of the given reaction is to be stated.

Concept introduction:

Organolithium reagents are very reactive organometallic compounds. These compounds attack directly on the carbonyl carbon of carbonyl compounds. The organolithium compounds are very strong base and therefore, undergo acid-base reactions very quickly.

Expert Solution & Answer

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Answer 4

Question

Chapter 20, Problem 20.51AP

Interpretation Introduction

(a)

Interpretation:

A mechanism for the reaction of two equivalents of the methyllithium with carboxylic acids to produce ketones is to be stated.

Concept introduction:

Organolithium reagents are very reactive organometallic compounds. These compounds attack directly on the carbonyl carbon of carbonyl compounds. The organolithium compounds are very strong base and therefore, undergo acid-base reactions very quickly.

Interpretation Introduction

(b)

Interpretation:

The product of the given reaction is to be stated.

Concept introduction:

Organolithium reagents are very reactive organometallic compounds. These compounds attack directly on the carbonyl carbon of carbonyl compounds. The organolithium compounds are very strong base and therefore, undergo acid-base reactions very quickly.

Expert Solution & Answer

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Answer 5

Chapter 20, Problem 20.51AP

Interpretation Introduction

(a)

Interpretation:

A mechanism for the reaction of two equivalents of the methyllithium with carboxylic acids to produce ketones is to be stated.

Concept introduction:

Organolithium reagents are very reactive organometallic compounds. These compounds attack directly on the carbonyl carbon of carbonyl compounds. The organolithium compounds are very strong base and therefore, undergo acid-base reactions very quickly.

Interpretation Introduction

(b)

Interpretation:

The product of the given reaction is to be stated.

Concept introduction:

Organolithium reagents are very reactive organometallic compounds. These compounds attack directly on the carbonyl carbon of carbonyl compounds. The organolithium compounds are very strong base and therefore, undergo acid-base reactions very quickly.

Answer 6

Chapter 20, Problem 20.51AP

Interpretation Introduction

(a)

Interpretation:

A mechanism for the reaction of two equivalents of the methyllithium with carboxylic acids to produce ketones is to be stated.

Concept introduction:

Organolithium reagents are very reactive organometallic compounds. These compounds attack directly on the carbonyl carbon of carbonyl compounds. The organolithium compounds are very strong base and therefore, undergo acid-base reactions very quickly.

Answer 7

Chapter 20, Problem 20.51AP

Interpretation Introduction

(a)

Interpretation:

A mechanism for the reaction of two equivalents of the methyllithium with carboxylic acids to produce ketones is to be stated.

Concept introduction:

Organolithium reagents are very reactive organometallic compounds. These compounds attack directly on the carbonyl carbon of carbonyl compounds. The organolithium compounds are very strong base and therefore, undergo acid-base reactions very quickly.

Answer 8

Interpretation Introduction

(b)

Interpretation:

The product of the given reaction is to be stated.

Concept introduction:

Organolithium reagents are very reactive organometallic compounds. These compounds attack directly on the carbonyl carbon of carbonyl compounds. The organolithium compounds are very strong base and therefore, undergo acid-base reactions very quickly.

Answer 9

Interpretation Introduction

(b)

Interpretation:

The product of the given reaction is to be stated.

Concept introduction:

Organolithium reagents are very reactive organometallic compounds. These compounds attack directly on the carbonyl carbon of carbonyl compounds. The organolithium compounds are very strong base and therefore, undergo acid-base reactions very quickly.

Answer 10

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Answer 11

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Answer 12

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Answer 13

Ch. 20 - Prob. 20.1P Ch. 20 - Prob. 20.2P Ch. 20 - Prob. 20.3P Ch. 20 - Prob. 20.4P Ch. 20 - Prob. 20.5P Ch. 20 - Prob. 20.6P Ch. 20 - Prob. 20.7P Ch. 20 - Prob. 20.8P Ch. 20 - Prob. 20.9P Ch. 20 - Prob. 20.10P

Solution Summary: The author explains the mechanism for the reaction of two equivalents of the methyllithium with carboxylic acids to produce ketones.

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Chapter 20 Solutions