Fundamentals of General, Organic and Biological Chemistry Volume 1, 5th custom edition for Spokane Community College
Fundamentals of General, Organic and Biological Chemistry Volume 1, 5th custom edition for Spokane Community College
1st Edition
ISBN: 9781323562789
Author: John McMurry, David Ballantine, Carl Hoeger
Publisher: Pearson Education
Question
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Chapter 24, Problem 24.47AP

(a)

Interpretation Introduction

Interpretation:

The products of the given step in the fatty acid oxidation of hexanoic acid should be determined.

Concept introduction:

Fatty acids are aliphatic mono-carboxylic acids that are mostly obtained from the hydrolysis of natural fats and oils. They have a general formula R(CH2)nCOOH, n is mostly an even number of carbon atoms (4 to 20) with a few exceptions that have an odd number

Fatty acids in the body are mostly oxidized by β oxidation.

β-oxidation is the oxidation and splitting of two carbon units at β- carbon atom. This results in sequential removal of 2 carbon fragments as acetyl CoA until the complete oxidation of fatty acids.

The four important steps of β-oxidation are,

Step 1: Dehydrogenation of the fatty acyl-CoA to make ‘trans’ double bond between α and β carbon.

  • Short, medium and long chain acyl-CoAdehydrogenases
  • Electron removed transferred to FAD

Step 2: Hydration of the double bond.

Step 3: Dehydrogenation of the β-hydroxyl group to a ketone.

  • Electron removed transferred to NAD+

Step 4: Acylation-addition of CoA and production of and production of acetyl-CoA

(b)

Interpretation Introduction

Interpretation:

The products of the given step in the fatty acid oxidation of hexanoic acid should be determined.

Concept introduction:

Fatty acids are aliphatic mono-carboxylic acids that are mostly obtained from the hydrolysis of natural fats and oils. They have a general formula R(CH2)nCOOH, n is mostly an even number of carbon atoms (4 to 20) with a few exceptions that have an odd number

Fatty acids in the body are mostly oxidized by β oxidation.

β-oxidation is the oxidation and splitting of two carbon units at β- carbon atom. This results in sequential removal of 2 carbon fragments as acetyl CoA until the complete oxidation of fatty acids.

The four important steps of β-oxidation are,

Step 1: Dehydrogenation of the fatty acyl-CoA to make ‘trans’ double bond between α and β carbon.

  • Short, medium and long chain acyl-CoAdehydrogenases
  • Electron removed transferred to FAD

Step 2: Hydration of the double bond.

Step 3: Dehydrogenation of the β-hydroxyl group to a ketone.

  • Electron removed transferred to NAD+

Step 4: Acylation-addition of CoA and production of and production of acetyl-CoA

(c)

Interpretation Introduction

Interpretation:

The products of the given step in the fatty acid oxidation of hexanoic acid should be determined.

Concept introduction:

Fatty acids are aliphatic mono-carboxylic acids that are mostly obtained from the hydrolysis of natural fats and oils. They have a general formula R(CH2)nCOOH, n is mostly an even number of carbon atoms (4 to 20) with a few exceptions that have an odd number

Fatty acids in the body are mostly oxidized by β oxidation.

β-oxidation is the oxidation and splitting of two carbon units at β- carbon atom. This results in sequential removal of 2 carbon fragments as acetyl CoA until the complete oxidation of fatty acids.

The four important steps of β-oxidation are,

Step 1: Dehydrogenation of the fatty acyl-CoA to make ‘trans’ double bond between α and β carbon.

  • Short, medium and long chain acyl-CoAdehydrogenases
  • Electron removed transferred to FAD

Step 2: Hydration of the double bond.

Step 3: Dehydrogenation of the β-hydroxyl group to a ketone.

  • Electron removed transferred to NAD+

Step 4: Acylation-addition of CoA and production of and production of acetyl-CoA

(d)

Interpretation Introduction

Interpretation:

The products of the given step in the fatty acid oxidation of hexanoic acid should be determined.

Concept introduction:

Fatty acids are aliphatic mono-carboxylic acids that are mostly obtained from the hydrolysis of natural fats and oils. They have a general formula R(CH2)nCOOH, n is mostly an even number of carbon atoms (4 to 20) with a few exceptions that have an odd number

Fatty acids in the body are mostly oxidized by β oxidation.

β-oxidation is the oxidation and splitting of two carbon units at β- carbon atom. This results in sequential removal of 2 carbon fragments as acetyl CoA until the complete oxidation of fatty acids.

The four important steps of β-oxidation are,

Step 1: Dehydrogenation of the fatty acyl-CoA to make ‘trans’ double bond between α and β carbon.

  • Short, medium and long chain acyl-CoAdehydrogenases
  • Electron removed transferred to FAD

Step 2: Hydration of the double bond.

Step 3: Dehydrogenation of the β-hydroxyl group to a ketone.

  • Electron removed transferred to NAD+

Step 4: Acylation-addition of CoA and production of and production of acetyl-CoA

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Chapter 24 Solutions

Fundamentals of General, Organic and Biological Chemistry Volume 1, 5th custom edition for Spokane Community College

Ch. 24.6 - Prob. 24.8PCh. 24.6 - Prob. 24.9PCh. 24.7 - Prob. 24.4CIAPCh. 24.7 - Prob. 24.5CIAPCh. 24.7 - Prob. 24.6CIAPCh. 24.7 - What is atherosclerosis?Ch. 24.7 - Prob. 24.8CIAPCh. 24 - Oxygen is not a reactant in the oxidation of...Ch. 24 - Prob. 24.12UKCCh. 24 - Prob. 24.13UKCCh. 24 - Prob. 24.14UKCCh. 24 - Prob. 24.15UKCCh. 24 - Prob. 24.16UKCCh. 24 - Prob. 24.17UKCCh. 24 - Prob. 24.18UKCCh. 24 - Prob. 24.19APCh. 24 - Prob. 24.20APCh. 24 - Prob. 24.21APCh. 24 - Prob. 24.22APCh. 24 - Prob. 24.23APCh. 24 - Prob. 24.24APCh. 24 - Prob. 24.25APCh. 24 - Prob. 24.26APCh. 24 - Prob. 24.27APCh. 24 - Prob. 24.28APCh. 24 - Prob. 24.29APCh. 24 - Prob. 24.30APCh. 24 - Prob. 24.33APCh. 24 - Prob. 24.34APCh. 24 - Prob. 24.35APCh. 24 - Prob. 24.36APCh. 24 - Prob. 24.37APCh. 24 - Prob. 24.38APCh. 24 - Prob. 24.39APCh. 24 - Prob. 24.40APCh. 24 - Prob. 24.41APCh. 24 - Prob. 24.42APCh. 24 - Prob. 24.43APCh. 24 - Prob. 24.44APCh. 24 - Prob. 24.45APCh. 24 - Prob. 24.46APCh. 24 - Prob. 24.47APCh. 24 - Prob. 24.48APCh. 24 - Prob. 24.49APCh. 24 - Prob. 24.50APCh. 24 - Prob. 24.51APCh. 24 - Prob. 24.52APCh. 24 - Prob. 24.53APCh. 24 - Individuals suffering from ketoacidosis have...Ch. 24 - Prob. 24.55APCh. 24 - Prob. 24.56APCh. 24 - Prob. 24.57APCh. 24 - Prob. 24.58APCh. 24 - Why are fatty acids generally composed of an even...Ch. 24 - Prob. 24.60APCh. 24 - Prob. 24.62APCh. 24 - Prob. 24.63APCh. 24 - Prob. 24.64CPCh. 24 - Prob. 24.66CPCh. 24 - Prob. 24.67CPCh. 24 - Prob. 24.68CPCh. 24 - Prob. 24.70GPCh. 24 - In the synthesis of cholesterol, acetyl-CoA is...Ch. 24 - Prob. 24.72GP
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