Brock Biology of Microorganisms, Books a la Carte Plus Mastering Microbiology with Pearson eText -- Access Card Package (15th Edition)
Brock Biology of Microorganisms, Books a la Carte Plus Mastering Microbiology with Pearson eText -- Access Card Package (15th Edition)
15th Edition
ISBN: 9780134603940
Author: Michael T. Madigan, Kelly S. Bender, Daniel H. Buckley, W. Matthew Sattley, David A. Stahl
Publisher: PEARSON
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Chapter 26.5, Problem 1CR

Pathogens may colonize host tissues when appropriate nutrients and growth conditions are present, such as on mucosal surfaces, especially where the composition of the normal microbiota has been altered. Innate responses to microbial invasion and tissue damage are initiated by the release of chemokines, which recruit phagocytes and other immune cells to sites of infection.

Describe a scenario in which microorganisms invade body tissues. What factors allow for the migration of phagocytes to sites of infection?

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Which of the following statements are TRUE about the process of inflammation? (Select all that apply)     Inflammation can occur with only the innate immune response involved.     Leukocytes or white blood cells are found everywhere in the body to carry out inflammation as needed     Growth factor from non-skin cells is responsible for the formation of scar tissue in place of the damaged skin cells     The increase of warmed blood to a site of injury comes from the hypothalamus      Phagocytes engulf invading microbes and dead white blood cells      Phagocytosis is used during inflammation to make sure there is no debris
Although the complement cascade can be initiated by antibodies bound to the surface of a pathogen, complement activation is generally considered to be an innate immune response. This is because: Two of the three pathways for complement activation are initiated by constitutively produced recognition molecules that directly interact with microbial surfaces. When the complement cascade leads to the formation of a membrane-attack complex, the pathogen is killed. Several of the soluble products generated by complement activation lead promote the inflammatory response. Complement proteins bound to the pathogen promote uptake and destruction by phagocytic cells. The C3 convertase is only produced when complement activation is initiated by antibody binding to a pathogen.
Macrophages and neutrophils both contribute to extracellular pathogen protection. Describe their common characteristics, differences in structure and function, and if one were eliminated from the innate immune response, explain which one would be more detrimental to the body and why.

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Brock Biology of Microorganisms, Books a la Carte Plus Mastering Microbiology with Pearson eText -- Access Card Package (15th Edition)

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