Brock Biology of Microorganisms, Books a la Carte Plus Mastering Microbiology with Pearson eText -- Access Card Package (15th Edition)
15th Edition
ISBN: 9780134603940
Author: Michael T. Madigan, Kelly S. Bender, Daniel H. Buckley, W. Matthew Sattley, David A. Stahl
Publisher: PEARSON
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Chapter 26, Problem 4AQ
Summary Introduction
To explain:
The reason that why complement system is a critical component of antibody-mediated defense. Also, explain possible outcomes in a person if complement component C3, C5, and factor B of the alternative pathway and mannose-binding lectin pathway is absent in that particular individual.
Concept introduction:
The complement system comprises many soluble proteins which help in catalyzing the process of cell lysis and bacterial opsonization. The complement system is triggered by various types of interactions with antibodies and nonspecific activators such as mannose-binding lectin.
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Students have asked these similar questions
Which of these statements about complement proteins C3a and C5a is false?a. They are released during the complement fixation process.b. They stimulate chemotaxis of phagocytic cells.c. They promote the activity of phagocytic cells.d.They produce pores in the victim plasma membrane.
Which of the following does not describe the outcome of complement activation?
a. chemotaxis
b. opsonization
c. vasoconstriction
d. proteolysis
e. membrane permeabilization.
All of the following are involved in the alternative pathway of complement activation except _____.
a. factor B
b. factor D
c. factor P (properdin)
d. C4
e. C5.
Chapter 26 Solutions
Brock Biology of Microorganisms, Books a la Carte Plus Mastering Microbiology with Pearson eText -- Access Card Package (15th Edition)
Ch. 26.1 - What major class of immune cells mediates an...Ch. 26.1 - Prob. 2MQCh. 26.1 - Compare and contrast the major features of innate...Ch. 26.2 - Describe host tissue specificity for pathogens.Ch. 26.2 - Identify physical and chemical barriers to...Ch. 26.2 - What other factors may control the outcome of an...Ch. 26.2 - Identify at least four mechanisms by which a...Ch. 26.3 - Describe the circulation of a leukocyte from the...Ch. 26.3 - What soluble molecules determine whether a...Ch. 26.3 - Cells involved in innate and adaptive immunity...
Ch. 26.4 - How does the development of B, T, and NK cells...Ch. 26.4 - Distinguish between the primary lymphoid organs...Ch. 26.4 - Leukocytes are differentiated white blood cells...Ch. 26.5 - Although technically not part of the immune...Ch. 26.5 - Describe the mechanisms by which circulating...Ch. 26.5 - Pathogens may colonize host tissues when...Ch. 26.6 - Identify a PAMP shared by a group of...Ch. 26.6 - Outline the general features of a signal...Ch. 26.6 - Innate recognition of common pathogens occurs...Ch. 26.7 - Identify the mechanism used by phagocytes to...Ch. 26.7 - Describe several reasons why phagocytes are not...Ch. 26.7 - Phagocytosis is the engulfing of infectious...Ch. 26.8 - Prob. 1MQCh. 26.8 - Identify the major symptoms of localized...Ch. 26.8 - Fever and inflammation, characterized by pain,...Ch. 26.9 - In what ways does the classical pathway of...Ch. 26.9 - What is opsonization, and how does opsonization...Ch. 26.9 - Why are the mannose-binding lectin and alternative...Ch. 26.9 - The complement system is composed of soluble...Ch. 26.10 - Prob. 1MQCh. 26.10 - Prob. 2MQCh. 26.10 - Prob. 1CRCh. 26 - Prob. 1AQCh. 26 - Describe the potential problems that would arise...Ch. 26 - Prob. 3AQCh. 26 - Prob. 4AQ
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- Complement proteins function in defense by _______. a. neutralizing toxins b. enhancing resident bacteria c. promoting inflammation d. forming pores that cause pathogens to disintegrate e. both a and b f. both c and darrow_forwardThe Adaptive Immune Response Is a Specific Defense Against Infection Name the class of molecules that includes antibodies, and name the five groups that make up this class.arrow_forwardThe Complement System Kills Microorganisms The complement system supplements the inflammatory response by directly killing microorganisms. Describe the life cycle of complement proteins, from their synthesis in the liver to their activity at the site of an infection.arrow_forward
- What triggers the alternative pathway for complement activation?arrow_forwardTwo of the major actions of complement are a. increased inflammatory response and cytolysis. b. recognition and destruction of a specific antigen and cytolysis. c. production of antibody and increased inflammatory response. d. release of cytokines to increase the immune response and production of antibody.arrow_forwardSome bacterial cells avoid the killing effects of activated complement proteins. How might they do this?arrow_forward
- In your own personal understanding, why are complements important in cellular and humoral mediated immunity? please answer in a minimum of 5 sentences.arrow_forwardParoxysmal nocturnal hemoglobinuria is a disease characterized by lysis of red blood cells, which results from the loss of____ on the cell surface, making them susceptible to the____ complement pathway.arrow_forwardThree effects of complement activation: (1) inflammation (2) opsonization (3) cytolysis of pathogens. Describe the three effects in at least one complete sentence for each. You should clearly explain *how* complement activation results in the three different effects.arrow_forward
- Which pathway of complement activation is depicted in this figure?arrow_forwardWhat clinical symptoms can an inherited deficiency in complement components C3 or C4 lead to?arrow_forwardInflammation is the hallmark of an activated immune response. Explain how inflammation is triggered by both innate and adaptive immune mechanisms. Are the inflammatory cells the same for both methods of activation? Why does inflammation subside as an infection is controlled?arrow_forward
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