(a)
Interpretation:
The explanation for the fact that the given procedure to synthesis the dipeptide
Concept introduction:
The chemical compounds in which carbon is bonded with the acidic and basic group along with hydrocarbon side chain are known as amino acids. The amino acids are classified into acidic, basic, polar, non-polar, essential, and non-essential categories. The three-word abbreviation or one-word abbreviation is used for amino acids.
(b)
Interpretation:
The explanation for the fact that the given procedure to synthesis the dipeptide
Concept introduction:
The chemical compounds in which carbon is bonded with the acidic and basic group along with hydrocarbon side chain are known as amino acids. The amino acids are classified into acidic, basic, polar, non-polar, essential, and non-essential categories. The three-word abbreviation or one-word abbreviation is used for amino acids.
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EBK ORGANIC CHEMISTRY
- Write the complete structures for the following peptides. Tell whether each peptide is acidic, basic, or neutral.(a) methionylthreonine (b) threonylmethionine(c) arginylaspartyllysine (d) Glu-Cys-Glnarrow_forwardindicate the RIGHT alternative: (a) The Zwitterion form of an amino acid exists only at a point pH value. (b) In a peptide bond there is free rotation at the C-N bond. (c) In a polypeptide, the terminal carboxyl group may be present in its amide form. (d) At a pH greater than pI, an amino acid tends to move towards the cathode in an electrophoresis. (e) At any pH below pI, the predominant form of an amino acid is negatively charged.arrow_forwardDraw the complete structures of the following peptides:(a) Thr-Phe-Met (b) serylarginylglycylphenylalanine (c) IMQDK (d) ELVISarrow_forward
- Draw three-dimensional representations of the following amino acids.(a) l-phenylalaninearrow_forwardTreatment of a new protein with dansyl chloride reveals two (2) dansyl-labelled derivatives of amino acids, alanine and methionine. What can you deduce about the structure of the proteinfrom these results?arrow_forwardSomatostatin is a tetradecapeptide of the hypothalamus that inhibits the release of pituitary growth hormone. Its amino acid sequence has been determined by a combination of Edman degradations and enzymic hydrolysis experiments. On the basis of the following data, deduce the primary structure of somatostatin: 1. Edman degradation gave PTH-Ala. 2. Selective hydrolysis gave peptides having the following indicated sequences: Phe-Trp Thr-Ser-Cys Lys-Thr-Phe Thr-Phe-Thr-Ser-Cys Asn-Phe-Phe-Trp-Lys Ala-Gly-Cys-Lys-Asn-Phe 3. Somatostatin has a disulfide bridge.arrow_forward
- The peptide Proline-Serine-Alanine-Phenylalanine-Glutamine is present at pH 7. Draw the peptide and include stereochemistry.arrow_forwardDraw zwitterion forms of these amino acids. (a) Valine (b) Phenylalanine (c) Glutaminearrow_forwardThere is a hexapeptide, and its primary structure is written down according to the following experimental results, and the analysis process is briefly written down: (1) DNP-Ala was obtained by DNFB reaction; (2) DNP-Ile was obtained by reaction with DNFB after hydrazine hydrolysis; (3) Two tripeptides were obtained by reaction with cyanogen bromide, then DNP-Leu and DNP-Ala were obtained by reaction with DNFB; (4) Fragments containing 1, 2 and 3 amino acids were obtained by trypsin hydrolysis, and the Sakakuchi reaction of the last two fragments was positive.arrow_forward
- Explain what is meant by the following :(i) peptide linkage(ii) pyranose structure of glucosearrow_forwardDraw three-dimensional representations of the following amino acids.(a) l-phenylalanine (b) l-histidine (c) d-serine (d) l-tryptophanDraw three-dimensional representations of the following amino acids.(a) l-phenylalanine (b) l-histidine (c) d-serine (d) l-tryptophanarrow_forwardA normal polypeptide and a mutant of the polypeptide were hydrolyzed by an endopeptidase under the same conditions. The normal and mutant poly peptide differ by one amino acid. The fingerprints of the peptides obtained from the two polypeptides are shown below. What kind of amino acid substitution occurred as a result of the mutation? (That is, is the substituted amino acid more or less polar than the original amino acid? Is its pI lower or higher?)arrow_forward