Biochemistry
Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
Question
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Chapter 31, Problem 47P
Interpretation Introduction

(a)

Interpretation:

Effects on eIF-4 helicase activity in the presence of eIF-4H should be determined.

Concept introduction:

Eukaryotic initiation factors (eIFs) are the proteins, which are used during the initiation of the eukaryotic translation process. The function of these proteins is to stabilize the ribosomal complexes that are near the start codon on the mRNA strand.

Interpretation Introduction

(b)

Interpretation:

The importance of measuring the helicase activity of eIF-4H as control should be determined.

Concept introduction:

Eukaryotic initiation factors (eIFs) are the proteins, which are used during the initiation of the eukaryotic translation process. The function of these proteins is to stabilize the ribosomal complexes that are near the start codon on the mRNA strand.

Interpretation Introduction

(c)

Interpretation:

The ratio of eIF-4H and eIF-4 should be determined to attain optimal activity.

Concept introduction:

Eukaryotic initiation factors (eIFs) are the proteins, which are used during the initiation of eukaryotic translation process. The function of these proteins is to stabilize the ribosomal complexes that are near the start codon on the mRNA strand.

Interpretation Introduction

(d)

Interpretation:

The varying effect f eIF-4H with helix stability should be determined.

Concept introduction:

Eukaryotic initiation factors (eIFs) are the proteins, which are used during the initiation of the eukaryotic translation process. The function of these proteins is to stabilize the ribosomal complexes that are near the start codon on the mRNA strand.

Interpretation Introduction

(e)

Interpretation:

The effect of eIF-4H on the helicase activity of eIF-4A should be determined.

Concept introduction:

Eukaryotic initiation factors (eIFs) are the proteins, which are used during the initiation of eukaryotic translation process. The function of these proteins is to stabilize the ribosomal complexes that are near the start codon on the mRNA strand.

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