5'-ATGTCCACTGCGGTCCTGGAAAACCCAGGC-3’ wild-type allele 3'-TACAGGTGACGCCAGGACCTTTTGGGTCCG-5’ 5'-GTGTCCACTGCGGTCCTGGAAAACCCAGGC-3’ allele C 3'-CACAGGTGACGCCAGGACCTTTTGGGTCCG-5’ • (a) What type of mutation is allele C: insertion, deletion, substitution, or inversion? (b) The sequence shown above is first exon, and the first codon is the start codon. Given what effect does the mutation have on the transcribed mRNA? (c) What effect does the mutation have on the translated amino acid sequence?

5'-ATGTCCACTGCGGTCCTGGAAAACCCAGGC-3’ wild-type allele 3'-TACAGGTGACGCCAGGACCTTTTGGGTCCG-5’ 5'-GTGTCCACTGCGGTCCTGGAAAACCCAGGC-3’ allele C 3'-CACAGGTGACGCCAGGACCTTTTGGGTCCG-5’ • (a) What type of mutation is allele C: insertion, deletion, substitution, or inversion? (b) The sequence shown above is first exon, and the first codon is the start codon. Given what effect does the mutation have on the transcribed mRNA? (c) What effect does the mutation have on the translated amino acid sequence?

Basic Clinical Laboratory Techniques 6E

6th Edition

ISBN:9781133893943

Author:ESTRIDGE

Publisher:ESTRIDGE

Chapter1: The Clinical Laboratory

Section1.9: Quality Assessment

Problem 3CS

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