Concept explainers
To analyze:
A wild type protein has a partial amino acid sequence-
And the mutant sequence for the same portion is-
a. From the given sequences, describe the type of mutation.
b. Determine the wild type DNA template strand.
To represent purines- Use (A/G) and pyrimidines with (T/C); use N for any
Introduction:
Gene mutations are rare and random changes in the DNA sequence which result in the alteration ofPolypeptide composition and protein function. Mutations may also outcome in
The frame-shift mutation is the shift in the open reading frame of a coding sequence caused by the addition or deletion of the base pair. The mutation will result in mutant polypeptide. This amino acid sequence will have an altered sequence.
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GENETIC ANALYSIS: AN INTEG. APP. W/MAS
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