Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 15.6, Problem 1COMQ
The binding of iron regulatory protein (IRP) to the iron response element (IRE) in the 5′ region of the ferritin mRNA results in the
a. inhibition of translation of the ferritin mRNA.
b. stimulation of translation of the ferritin mRNA.
c. degradation of the ferritin mRNA.
d. both a and c.
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The binding of iron regulatory protein (IRP) to the iron response element (IRE) in the 5′-untranslated region of the ferritin mRNA results ina. inhibition of translation of the ferritin mRNA.b. stimulation of translation of the ferritin mRNA.c. degradation of the ferritin mRNA.d. both a and c.
A mutation that changes the sequence of nucleotides in a promoter would result in a change in
a.
The amino acid sequence of the corresponding protein
b.
The base sequence of the corresponding mRNA
c.
How frequently the corresponding gene is transcribed
d.
The fidelity of translation of the corresponding mRNA
1 points
Within a cell, the amount of protein made using a given mRNA molecule depends partly on
A. the presence of certain transcription factors.
B. the rate at which the mRNA is degraded.
C. the degree of DNA methylation.
D. the number of introns present in the mRNA.
please explain which is correct and incorrect and why
Chapter 15 Solutions
Genetics: Analysis and Principles
Ch. 15.1 - 1. Combinatorial control refers to the phenomenon...Ch. 15.1 - 2. A regulatory transcription factor protein...Ch. 15.1 - 3. A bidirectional enhancer has the following...Ch. 15.1 - 4. Regulatory transcription factors can be...Ch. 15.2 - 1. A chromatin-remodeling complex may
a. change...Ch. 15.2 - Prob. 2COMQCh. 15.2 - 3. Which of the following characteristics is...Ch. 15.2 - 4. Transcriptional activation of eukaryotic genes...Ch. 15.3 - How can methylation affect transcription? a. It...Ch. 15.3 - 2. The process in which completely unmethylated...
Ch. 15.4 - Prob. 1COMQCh. 15.5 - The overall goal of the ENCODE Project is a. to...Ch. 15.6 - The binding of iron regulatory protein (IRP) to...Ch. 15 - Discuss the common points of control in eukaryotic...Ch. 15 - 2. Discuss the structure and function of...Ch. 15 - 3. What is meant by the term transcription factor...Ch. 15 - What are the functions of transcriptional...Ch. 15 - 5. Is each of the following statements true or...Ch. 15 - 6. Transcription factors usually contain one or...Ch. 15 - Prob. 7CONQCh. 15 - Prob. 8CONQCh. 15 - 9. Let’s suppose a mutation in the glucocorticoid...Ch. 15 - Prob. 10CONQCh. 15 - Prob. 11CONQCh. 15 - Prob. 12CONQCh. 15 - 13. Transcription factors such as the...Ch. 15 - An enhancer, located upstream from a gene, has the...Ch. 15 - 15. The DNA-binding domain of each CREB protein...Ch. 15 - The gene that encodes the enzyme called tyrosine...Ch. 15 - Prob. 17CONQCh. 15 - 18. What is a histone variant?
Ch. 15 - Prob. 19CONQCh. 15 - 20. What is meant by the term histone code? With...Ch. 15 - Prob. 21CONQCh. 15 - Histones are thought to be displaced as RNA...Ch. 15 - 23. What is an insulator? Describe two different...Ch. 15 - 24. What is DNA methylation? When we say that DNA...Ch. 15 - Lets suppose that a vertebrate organism carries a...Ch. 15 - 26. What is a CpG island? Where would you expect...Ch. 15 - Describe how the binding of iron regulatory...Ch. 15 - 1. Briefly describe the method of chromatin...Ch. 15 - Researchers can isolate a sample of cells, such as...Ch. 15 - Prob. 3EQCh. 15 - Prob. 4EQCh. 15 - Prob. 5EQCh. 15 - 6. As described in Chapter 21, an electrophoretic...Ch. 15 - Prob. 7EQCh. 15 - 1. Explain how DNA methylation could be used to...Ch. 15 - 2. Enhancers can occur almost anywhere in DNA and...
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- What strategy does a genetically encoded calcium indicator look like to allow fluorescence imaging of only one cell type in an acute slice of the brain? A.The use of fluorescent protein expression inhibitors in other cells B.The injection of a recombinant virus causing the death of other cells C.The use of a promoter specific to these cells D.Activation of membrane receptors specific to these cellsarrow_forwardIf a gene sequence is more tightly coiled around histones, then which of the following is the most likely consequence? A) This gene is more likely to undergo mutation as it is being expressed B) This gene is unlikely to be transcribed while in this conformation C) This gene will be transcribed often while in this conformation D) This gene will be translated more efficiently .arrow_forwardA genetic researcher notices that individuals with a particular genetic disease have a shortened version of key protein involved in the diseased biochemical pathway. Which of the following mutations is most likely to result in the premature termination of protein synthesis? A. The disease is caused by a silent mutation. B. The disease is caused by a frameshift mutation. C. The disease is caused by a missense mutation. D. The disease is caused by a nonsense mutation.arrow_forward
- A scientist studies the production of a key digestive enzyme in silk moths. The moths have one gene for this enzyme, and the scientist extracts mRNA transcribed from this gene as well as protein translated from it. The gene has three introns in its sequence. If the researcher compares mRNA from inside the nucleus to mRNA from the ribosomes, what will be found? A. less mRNA in the nucleus B. shorter mRNA in the ribosomes C. identical mRNAs in both places D. mRNA covalently attached to protein in the nucleusarrow_forwardWhich of the following is true of transcription factors? A)The same transcription factors are found in all cell types. B)They can increase or decrease gene expression. C)They are a type of cis-acting element. D)They bind only to promoters.arrow_forwarda piece of DNA is produced with 1) an enhancer from a gene expressed in the liver, 2) a promoter from a gene expressed in bone cells, and 3) exons and introns from a gene expressed in the brain introduction of this gene into a mouse then results in high levels of A) a brain protein in the liver B) a bone protein in the brain C) a brain protein in the bone D) a liver protein in the brain E) no protein would be madearrow_forward
- You are curious to identify the region of the gene X sequence that serves as an enhancer for gene expression. Design an experiment to investigate this issue.arrow_forwardYou hope to study a gene that codes for a neurotransmitter protein produced in human brain cells. You know the amino acid sequence of the protein. Explain how you might (a) identify what genes are expressed in a specific type of brain cell, (b) identify (and isolate) the neurotransmitter gene, (c) produce multiple copies of the gene for study, and (d) produce large quantities of the neurotransmitter for evaluation as a potential medication.arrow_forwardThe formation of peptide bonds between amino acids occurs _____. a. during transcription b. during the elongation step to translation c. during the assemble of the ribosome and mRNA d. while DNA is being replicatedarrow_forward
- If you imagine a messenger RNA molecule in the cytoplasm of a cell, which of the following will likely affect how much protein is made by translation of this message? A. The presence of appropriate snRNPs. B. The length of the polyA tail. C. The strength of hydrogen bonds holding the mRNA to ribosomal RNA. D. The ability of the mRNA to pair with itself to form a helix-turn-helix structure.arrow_forwardIf a mutation deletes the promoter in a eukrayotic gene, which of the following most accurately describes its consequence? A. There will be no mRNA or polypeptide made. B. The mRNA will be made but no polypeptide is made. C. The mRNA will not be processed properly. D. Nothing will happen. It is a silent mutation.arrow_forwardWhen would a ribosome bind to a promoter sequence? A) It wouldn't. A promoter is a DNA sequence, and ribosomes don't bind to DNA. B) When the ribosome needs to transcribe the gene that that promoter controls. C) When the ribosome is translating the DNA sequence of a gene. D) When there is a start codon (AUG) in the promoter sequence. .arrow_forward
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